SNP Detail For rs1534696
1.Mapping Information
Human SNP ID rs1534696
Human chromosome chr7
Human SNP position 26357619
Pig chromosome chr18
Pig SNP position 50858080
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region7p15.2
Chromosome idchr7
Chromosome position26357619
Reported geneSNX10
Mapped geneSNX10
Upstream gene id
Downstream gene id
SNP gene ids29887
Upstream gene distance
Downstream gene distance
SNP risk allelers1534696-C
SNPsrs1534696
Merged0
SNP id current1534696
Contextintron_variant
Intergenic0
Allele frequency0.4366
P value0.00000005
Pvalue mlog7.30102999566398
P value text(EA, women)
Or beta0.0266
%95 Ci[0.017-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region7p15.2
Chromosome idchr7
Chromosome position26357619
Reported geneSNX10
Mapped geneSNX10
Upstream gene id
Downstream gene id
SNP gene ids29887
Upstream gene distance
Downstream gene distance
SNP risk allelers1534696-C
SNPsrs1534696
Merged0
SNP id current1534696
Contextintron_variant
Intergenic0
Allele frequency0.4328
P value0.00000002
Pvalue mlog7.69897000433601
P value text(women)
Or beta0.0267
%95 Ci[0.017-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782