SNP Detail For rs1531590
1.Mapping Information
Human SNP ID rs1531590
Human chromosome chr8
Human SNP position 75124209
Pig chromosome chr4
Pig SNP position 66540531
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q21.13
Chromosome idchr8
Chromosome position75124209
Reported geneNR
Mapped geneLOC105375905
Upstream gene id
Downstream gene id
SNP gene ids105375905
Upstream gene distance
Downstream gene distance
SNP risk allelers1531590-C
SNPsrs1531590
Merged0
SNP id current1531590
Contextintergenic_variant
Intergenic0
Allele frequency0.227292733303651
P value0.000003
Pvalue mlog5.52287874528033
P value text(IGP26)
Or beta0.1794
%95 Ci[0.1-0.25] unit decrease
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848