SNP Detail For rs1529672
1.Mapping Information
Human SNP ID rs1529672
Human chromosome chr3
Human SNP position 25479091
Pig chromosome chr13
Pig SNP position 13999159
2.Annotation Information
PubMed ID21946350
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21946350
StudyGenome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Disease/TraitPulmonary function
Initial sample48,201 European ancestry individuals
Replication sample46,411 European ancestry individuals
Region3p24.2
Chromosome idchr3
Chromosome position25479091
Reported geneRARB
Mapped geneRARB
Upstream gene id
Downstream gene id
SNP gene ids5915
Upstream gene distance
Downstream gene distance
SNP risk allelers1529672-C
SNPsrs1529672
Merged0
SNP id current1529672
Contextintron_variant
Intergenic0
Allele frequency0.83
P value0.00000000000004
Pvalue mlog13.397940008672
P value text(FEV1/FVC)
Or beta0.048
%95 Ci[0.036-0.060] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitpulmonary function measurement, FEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001248
PubMed ID23284291
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23284291
StudyGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Disease/TraitPulmonary function (interaction)
Initial sample50,047 European ancestry individuals
Replication sampleNA
Region3p24.2
Chromosome idchr3
Chromosome position25479091
Reported geneRARB
Mapped geneRARB
Upstream gene id
Downstream gene id
SNP gene ids5915
Upstream gene distance
Downstream gene distance
SNP risk allelers1529672-?
SNPsrs1529672
Merged0
SNP id current1529672
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.00000000007
Pvalue mlog10.1549019599857
P value text(FEV1/FVC, Pack-years)
Or beta
%95 Ci
PlatformNR [~ 2500000] (imputed)
CNVN
Mapped traitFEV/FEC ratio
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST001784