SNP Detail For rs1514177
1.Mapping Information
Human SNP ID rs1514177
Human chromosome chr1
Human SNP position 74525718
Pig chromosome chr6
Pig SNP position 128516607
2.Annotation Information
PubMed ID23563607
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23563607
StudyGenome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Disease/TraitObesity
Initial sample93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls
Replication sample65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls
Region1p31.1
Chromosome idchr1
Chromosome position74525718
Reported geneTNNI3K
Mapped geneFPGT-TNNI3K, LOC105378803, TNNI3K
Upstream gene id
Downstream gene id
SNP gene ids100526835, 105378803, 51086
Upstream gene distance
Downstream gene distance
SNP risk allelers1514177-C
SNPsrs1514177
Merged0
SNP id current1514177
Contextintron_variant
Intergenic0
Allele frequency0.43
P value0.000000005
Pvalue mlog8.30102999566398
P value text(Obesity class I)
Or beta1.06
%95 Ci[NR]
PlatformAffymetrix, Illumina [~ 2800000] (imputed)
CNVN
Mapped traitobesity
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001073
Study accessionGCST001953