SNP Detail For rs1512285
1.Mapping Information
Human SNP ID rs1512285
Human chromosome chr4
Human SNP position 144529807
Pig chromosome chr8
Pig SNP position 89041453
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144529807
Reported geneIntergenic
Mapped geneLOC105377462
Upstream gene id
Downstream gene id
SNP gene ids105377462
Upstream gene distance
Downstream gene distance
SNP risk allelers1512285-A
SNPsrs1512285
Merged0
SNP id current1512285
Contextintergenic_variant
Intergenic0
Allele frequency0.428
P value0.00000005
Pvalue mlog7.30102999566398
P value text
Or beta0.05
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144529807
Reported geneIntergenic
Mapped geneLOC105377462
Upstream gene id
Downstream gene id
SNP gene ids105377462
Upstream gene distance
Downstream gene distance
SNP risk allelers1512285-A
SNPsrs1512285
Merged0
SNP id current1512285
Contextintergenic_variant
Intergenic0
Allele frequency0.425
P value0.000000002
Pvalue mlog8.69897000433601
P value text
Or beta0.011
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264