SNP Detail For rs149794616
1.Mapping Information
Human SNP ID rs149794616
Human chromosome chr3
Human SNP position 160837076
Pig chromosome chr13
Pig SNP position 108936046
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q25.33
Chromosome idchr3
Chromosome position160837076
Reported genePPM1L
Mapped genePPM1L
Upstream gene id
Downstream gene id
SNP gene ids151742
Upstream gene distance
Downstream gene distance
SNP risk allelers149794616-C
SNPsrs149794616
Merged0
SNP id current149794616
Contextintron_variant
Intergenic0
Allele frequency0.999
P value0.0000006
Pvalue mlog6.22184874961635
P value text(AA)
Or beta2.324
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region3q25.33
Chromosome idchr3
Chromosome position160837076
Reported genePPM1L
Mapped genePPM1L
Upstream gene id
Downstream gene id
SNP gene ids151742
Upstream gene distance
Downstream gene distance
SNP risk allelers149794616-C
SNPsrs149794616
Merged0
SNP id current149794616
Contextintron_variant
Intergenic0
Allele frequency0.999
P value0.000001
Pvalue mlog6
P value text(AA)
Or beta0.45
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264