Human SNP ID | rs1497406 |
---|---|
Human chromosome | chr1 |
Human SNP position | 16178825 |
Pig chromosome | chr6 |
Pig SNP position | 69615742 |
PubMed ID | 22001757 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22001757 |
Study | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. |
Disease/Trait | Liver enzyme levels (gamma-glutamyl transferase) |
Initial sample | Up to 52,350 European ancestry individuals, up to 8,739 Indian Asian ancestry individuals |
Replication sample | NA |
Region | 1p36.13 |
Chromosome id | chr1 |
Chromosome position | 16178825 |
Reported gene | EPHA2, RSG1 |
Mapped gene | LOC101927479 - ARHGEF19 |
Upstream gene id | 101927479 |
Downstream gene id | 128272 |
SNP gene ids | |
Upstream gene distance | 10609 |
Downstream gene distance | 19031 |
SNP risk allele | rs1497406-G |
SNPs | rs1497406 |
Merged | 0 |
SNP id current | 1497406 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.56 |
P value | 3E-19 |
Pvalue mlog | 18.5228787452803 |
P value text | |
Or beta | 3.8 |
%95 Ci | [2.70-4.80] % increase |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | serum gamma-glutamyl transferase measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004532 |
Study accession | GCST001277 |
PubMed ID | 22010049 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22010049 |
Study | Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. |
Disease/Trait | Gamma gluatamyl transferase levels |
Initial sample | 12,526 European ancestry individuals |
Replication sample | NA |
Region | 1p36.13 |
Chromosome id | chr1 |
Chromosome position | 16178825 |
Reported gene | intergenic |
Mapped gene | LOC101927479 - ARHGEF19 |
Upstream gene id | 101927479 |
Downstream gene id | 128272 |
SNP gene ids | |
Upstream gene distance | 10609 |
Downstream gene distance | 19031 |
SNP risk allele | rs1497406-T |
SNPs | rs1497406 |
Merged | 0 |
SNP id current | 1497406 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.41 |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | |
Or beta | 0.078 |
%95 Ci | [0.051-0.105] unit decrease |
Platform | Illumina [2380486] (imputed) |
CNV | N |
Mapped trait | serum gamma-glutamyl transferase measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004532 |
Study accession | GCST001307 |