SNP Detail For rs149709
1.Mapping Information
Human SNP ID rs149709
Human chromosome chr6
Human SNP position 37311157
Pig chromosome chr7
Pig SNP position 37796986
2.Annotation Information
PubMed ID24927181
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/24927181
StudyGenome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Disease/TraitAcne (severe)
Initial sample1,893 European ancestry cases, 5,132 European ancestry controls
Replication sample2,063 European ancestry cases, 1,970 European ancestry controls
Region6p21.2
Chromosome idchr6
Chromosome position37311157
Reported geneAK096023, AY927499, C6orf89, CCDC167, CPNE5, FGD2, FTSJD2, MDGA1, MIR4462, MTCH1, PI16, PIM1, PPIL1, RNF8, TBC1D22B, TMEM217, TRNA_Gln, ZFAND3
Mapped geneTBC1D22B
Upstream gene id
Downstream gene id
SNP gene ids55633
Upstream gene distance
Downstream gene distance
SNP risk allelers149709-C
SNPsrs149709
Merged0
SNP id current149709
Contextintron_variant
Intergenic0
Allele frequency0.2018
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.19
%95 Ci[1.08-1.30]
PlatformIllumina [7300000] (imputed)
CNVN
Mapped traitacne
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003894
Study accessionGCST002481