Human SNP ID | rs149709 |
---|---|
Human chromosome | chr6 |
Human SNP position | 37311157 |
Pig chromosome | chr7 |
Pig SNP position | 37796986 |
PubMed ID | 24927181 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/24927181 |
Study | Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. |
Disease/Trait | Acne (severe) |
Initial sample | 1,893 European ancestry cases, 5,132 European ancestry controls |
Replication sample | 2,063 European ancestry cases, 1,970 European ancestry controls |
Region | 6p21.2 |
Chromosome id | chr6 |
Chromosome position | 37311157 |
Reported gene | AK096023, AY927499, C6orf89, CCDC167, CPNE5, FGD2, FTSJD2, MDGA1, MIR4462, MTCH1, PI16, PIM1, PPIL1, RNF8, TBC1D22B, TMEM217, TRNA_Gln, ZFAND3 |
Mapped gene | TBC1D22B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 55633 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs149709-C |
SNPs | rs149709 |
Merged | 0 |
SNP id current | 149709 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.2018 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 1.19 |
%95 Ci | [1.08-1.30] |
Platform | Illumina [7300000] (imputed) |
CNV | N |
Mapped trait | acne |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003894 |
Study accession | GCST002481 |