SNP Detail For rs148071215
1.Mapping Information
Human SNP ID rs148071215
Human chromosome chr14
Human SNP position 82806309
Pig chromosome chr7
Pig SNP position 111880384
2.Annotation Information
PubMed ID25187353
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/25187353
StudyClozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Disease/TraitClozapine-induced agranulocytosis
Initial sample161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls
Replication sampleNA
Region14q31.1
Chromosome idchr14
Chromosome position82806309
Reported geneintergenic
Mapped geneLOC101928599 - LOC105370600
Upstream gene id101928599
Downstream gene id105370600
SNP gene ids
Upstream gene distance59585
Downstream gene distance205897
SNP risk allelers148071215-A
SNPsrs148071215
Merged0
SNP id current148071215
Contextintergenic_variant
Intergenic1
Allele frequency0.0217
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta4.3652
%95 Ci[3.80-4.93]
PlatformIllumina [8809853] (imputed)
CNVN
Mapped traitdrug-induced agranulocytosis, response to clozapine
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338
Study accessionGCST002595