Human SNP ID | rs148071215 |
---|---|
Human chromosome | chr14 |
Human SNP position | 82806309 |
Pig chromosome | chr7 |
Pig SNP position | 111880384 |
PubMed ID | 25187353 |
---|---|
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25187353 |
Study | Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. |
Disease/Trait | Clozapine-induced agranulocytosis |
Initial sample | 161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls |
Replication sample | NA |
Region | 14q31.1 |
Chromosome id | chr14 |
Chromosome position | 82806309 |
Reported gene | intergenic |
Mapped gene | LOC101928599 - LOC105370600 |
Upstream gene id | 101928599 |
Downstream gene id | 105370600 |
SNP gene ids | |
Upstream gene distance | 59585 |
Downstream gene distance | 205897 |
SNP risk allele | rs148071215-A |
SNPs | rs148071215 |
Merged | 0 |
SNP id current | 148071215 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.0217 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | |
Or beta | 4.3652 |
%95 Ci | [3.80-4.93] |
Platform | Illumina [8809853] (imputed) |
CNV | N |
Mapped trait | drug-induced agranulocytosis, response to clozapine |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0012235, http://purl.obolibrary.org/obo/GO_0097338 |
Study accession | GCST002595 |