SNP Detail For rs1473526
1.Mapping Information
Human SNP ID rs1473526
Human chromosome chr1
Human SNP position 218447405
Pig chromosome chr10
Pig SNP position 10510410
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218447405
Reported geneIntergenic
Mapped geneTGFB2 - LOC105372924
Upstream gene id7042
Downstream gene id105372924
SNP gene ids
Upstream gene distance2786
Downstream gene distance251159
SNP risk allelers1473526-T
SNPsrs1473526
Merged0
SNP id current1473526
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.406
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta0.045
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position218447405
Reported geneIntergenic
Mapped geneTGFB2 - LOC105372924
Upstream gene id7042
Downstream gene id105372924
SNP gene ids
Upstream gene distance2786
Downstream gene distance251159
SNP risk allelers1473526-T
SNPsrs1473526
Merged0
SNP id current1473526
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.408
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta0.011
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264