Human SNP ID | rs1464510 |
---|---|
Human chromosome | chr3 |
Human SNP position | 188394766 |
Pig chromosome | chr13 |
Pig SNP position | 135137351 |
PubMed ID | 18311140 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18311140 |
Study | Newly identified genetic risk variants for celiac disease related to the immune response. |
Disease/Trait | Celiac disease |
Initial sample | 767 European ancestry cases, 1,422 European ancestry controls |
Replication sample | 1,643 European ancestry cases, 3,406 European ancestry controls |
Region | 3q28 |
Chromosome id | chr3 |
Chromosome position | 188394766 |
Reported gene | LPP |
Mapped gene | LPP |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4026 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1464510-A |
SNPs | rs1464510 |
Merged | 0 |
SNP id current | 1464510 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.000000005 |
Pvalue mlog | 8.30102999566398 |
P value text | |
Or beta | 1.23 |
%95 Ci | [1.15-1.32] |
Platform | Illumina [310605] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000157 |
PubMed ID | 20190752 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20190752 |
Study | Multiple common variants for celiac disease influencing immune gene expression. |
Disease/Trait | Celiac disease |
Initial sample | 4,533 European ancestry cases, 10,750 European ancestry controls |
Replication sample | 4,918 European ancestry cases, 5,684 European ancestry controls |
Region | 3q28 |
Chromosome id | chr3 |
Chromosome position | 188394766 |
Reported gene | LPP |
Mapped gene | LPP |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4026 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1464510-A |
SNPs | rs1464510 |
Merged | 0 |
SNP id current | 1464510 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 3E-40 |
Pvalue mlog | 39.5228787452803 |
P value text | |
Or beta | 1.29 |
%95 Ci | [1.25-1.34] |
Platform | Illumina [292387] |
CNV | N |
Mapped trait | celiac disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001060 |
Study accession | GCST000612 |
PubMed ID | 20410501 |
Journal | N Engl J Med |
Link | www.ncbi.nlm.nih.gov/pubmed/20410501 |
Study | Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. |
Disease/Trait | Vitiligo |
Initial sample | 1,392 European ancestry cases, 2,629 European ancestry controls |
Replication sample | 647 European ancestry cases, 1,056 European ancestry controls, 183 European ancestry trios, 1,383 European ancestry individuals from 332 families |
Region | 3q28 |
Chromosome id | chr3 |
Chromosome position | 188394766 |
Reported gene | LPP |
Mapped gene | LPP |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 4026 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1464510-T |
SNPs | rs1464510 |
Merged | 0 |
SNP id current | 1464510 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.44 |
P value | 0.00000000001 |
Pvalue mlog | 11 |
P value text | |
Or beta | 1.31 |
%95 Ci | [1.21-1.41] |
Platform | Illumina [520460] |
CNV | N |
Mapped trait | Vitiligo |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004208 |
Study accession | GCST000662 |