SNP Detail For rs1464510
1.Mapping Information
Human SNP ID rs1464510
Human chromosome chr3
Human SNP position 188394766
Pig chromosome chr13
Pig SNP position 135137351
2.Annotation Information
PubMed ID18311140
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18311140
StudyNewly identified genetic risk variants for celiac disease related to the immune response.
Disease/TraitCeliac disease
Initial sample767 European ancestry cases, 1,422 European ancestry controls
Replication sample1,643 European ancestry cases, 3,406 European ancestry controls
Region3q28
Chromosome idchr3
Chromosome position188394766
Reported geneLPP
Mapped geneLPP
Upstream gene id
Downstream gene id
SNP gene ids4026
Upstream gene distance
Downstream gene distance
SNP risk allelers1464510-A
SNPsrs1464510
Merged0
SNP id current1464510
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000000005
Pvalue mlog8.30102999566398
P value text
Or beta1.23
%95 Ci[1.15-1.32]
PlatformIllumina [310605]
CNVN
Mapped traitceliac disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001060
Study accessionGCST000157
PubMed ID20190752
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/20190752
StudyMultiple common variants for celiac disease influencing immune gene expression.
Disease/TraitCeliac disease
Initial sample4,533 European ancestry cases, 10,750 European ancestry controls
Replication sample4,918 European ancestry cases, 5,684 European ancestry controls
Region3q28
Chromosome idchr3
Chromosome position188394766
Reported geneLPP
Mapped geneLPP
Upstream gene id
Downstream gene id
SNP gene ids4026
Upstream gene distance
Downstream gene distance
SNP risk allelers1464510-A
SNPsrs1464510
Merged0
SNP id current1464510
Contextintron_variant
Intergenic0
Allele frequency0.49
P value3E-40
Pvalue mlog39.5228787452803
P value text
Or beta1.29
%95 Ci[1.25-1.34]
PlatformIllumina [292387]
CNVN
Mapped traitceliac disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001060
Study accessionGCST000612
PubMed ID20410501
JournalN Engl J Med
Linkwww.ncbi.nlm.nih.gov/pubmed/20410501
StudyVariant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
Disease/TraitVitiligo
Initial sample1,392 European ancestry cases, 2,629 European ancestry controls
Replication sample647 European ancestry cases, 1,056 European ancestry controls, 183 European ancestry trios, 1,383 European ancestry individuals from 332 families
Region3q28
Chromosome idchr3
Chromosome position188394766
Reported geneLPP
Mapped geneLPP
Upstream gene id
Downstream gene id
SNP gene ids4026
Upstream gene distance
Downstream gene distance
SNP risk allelers1464510-T
SNPsrs1464510
Merged0
SNP id current1464510
Contextintron_variant
Intergenic0
Allele frequency0.44
P value0.00000000001
Pvalue mlog11
P value text
Or beta1.31
%95 Ci[1.21-1.41]
PlatformIllumina [520460]
CNVN
Mapped traitVitiligo
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004208
Study accessionGCST000662