SNP Detail For rs146173241
1.Mapping Information
Human SNP ID rs146173241
Human chromosome chr10
Human SNP position 116285226
Pig chromosome chr14
Pig SNP position 137760725
2.Annotation Information
PubMed ID26220383
JournalEpilepsy Res
Linkwww.ncbi.nlm.nih.gov/pubmed/26220383
StudyGWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy.
Disease/TraitEpilepsy and lamotrigine-induced maculopapular eruptions
Initial sample34 Korean ancestry cases, 1,080 Korean ancestry healthy controls
Replication sampleNA
Region10q25.3
Chromosome idchr10
Chromosome position116285226
Reported geneGFRA1, CCDC172
Mapped geneGFRA1 - CCDC172
Upstream gene id2674
Downstream gene id374355
SNP gene ids
Upstream gene distance11612
Downstream gene distance38878
SNP risk allelers146173241-?
SNPsrs146173241
Merged
SNP id current146173241
Contextintergenic_variant
Intergenic1
Allele frequency0.02
P value0.0000001
Pvalue mlog7
P value text
Or beta7.3
%95 Ci[NR]
PlatformAffymetrix [4893794] (imputed)
CNVN
Mapped traitresponse to lamotrigine, maculopapular eruption, epilepsy
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007661, http://www.ebi.ac.uk/efo/EFO_1001253, http://www.ebi.ac.uk/efo/EFO_0000474
Study accessionGCST002949