Human SNP ID | rs1446468 |
---|---|
Human chromosome | chr2 |
Human SNP position | 164106976 |
Pig chromosome | chr15 |
Pig SNP position | 78694720 |
PubMed ID | 21909110 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21909110 |
Study | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. |
Disease/Trait | Blood pressure |
Initial sample | 74,064 European ancestry individuals |
Replication sample | 48,607 European ancestry individuals |
Region | 2q24.3 |
Chromosome id | chr2 |
Chromosome position | 164106976 |
Reported gene | FIGN |
Mapped gene | FIGN - GRB14 |
Upstream gene id | 55137 |
Downstream gene id | 2888 |
SNP gene ids | |
Upstream gene distance | 370779 |
Downstream gene distance | 385430 |
SNP risk allele | rs1446468-T |
SNPs | rs1446468 |
Merged | 0 |
SNP id current | 1446468 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.53 |
P value | 0.000000000006 |
Pvalue mlog | 11.2218487496163 |
P value text | (Mean Arterial Pressure) |
Or beta | 0.336 |
%95 Ci | [0.24-0.44] mmHg decrease |
Platform | Affymetrix, Illumina, Perlegen [NR] (imputed) |
CNV | N |
Mapped trait | mean arterial pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
Study accession | GCST001236 |
PubMed ID | 26390057 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
Disease/Trait | Mean arterial pressure |
Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals |
Region | 2q24.3 |
Chromosome id | chr2 |
Chromosome position | 164106976 |
Reported gene | FIGN |
Mapped gene | FIGN - GRB14 |
Upstream gene id | 55137 |
Downstream gene id | 2888 |
SNP gene ids | |
Upstream gene distance | 370779 |
Downstream gene distance | 385430 |
SNP risk allele | rs1446468-T |
SNPs | rs1446468 |
Merged | 0 |
SNP id current | 1446468 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.4878 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | |
Or beta | 0.3106 |
%95 Ci | [0.18-0.44] mmHg decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
CNV | N |
Mapped trait | mean arterial pressure |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006340 |
Study accession | GCST003275 |