SNP Detail For rs1432295
1.Mapping Information
Human SNP ID rs1432295
Human chromosome chr2
Human SNP position 60839531
Pig chromosome chr3
Pig SNP position 85046176
2.Annotation Information
PubMed ID21037568
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21037568
StudyA genome-wide association study of Hodgkin__s lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).
Disease/TraitHodgkin__s lymphoma
Initial sample589 European ancestry cases, 5,199 European ancestry controls
Replication sample2,057 European ancestry cases, 3,416 European ancestry controls
Region2p16.1
Chromosome idchr2
Chromosome position60839531
Reported geneREL
Mapped genePAPOLG - LINC01185
Upstream gene id64895
Downstream gene id400957
SNP gene ids
Upstream gene distance37445
Downstream gene distance8229
SNP risk allelers1432295-G
SNPsrs1432295
Merged0
SNP id current1432295
Contextintron_variant
Intergenic1
Allele frequency0.4
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.22
%95 Ci[1.14-1.30]
PlatformIllumina [504374]
CNVN
Mapped traitHodgkins lymphoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000183
Study accessionGCST000851
PubMed ID24149102
JournalNat Commun
Linkwww.ncbi.nlm.nih.gov/pubmed/24149102
StudyVariation at 3p24.1 and 6q23.3 influences the risk of Hodgkin__s lymphoma.
Disease/TraitHodgkin__s lymphoma
Initial sample1,465 European ancestry cases, 6,417 European ancestry controls
Replication sample1,071 European ancestry cases, 953 cases, 1,853 controls
Region2p16.1
Chromosome idchr2
Chromosome position60839531
Reported geneNR
Mapped genePAPOLG - LINC01185
Upstream gene id64895
Downstream gene id400957
SNP gene ids
Upstream gene distance37445
Downstream gene distance8229
SNP risk allelers1432295-G
SNPsrs1432295
Merged0
SNP id current1432295
Contextintron_variant
Intergenic1
Allele frequency0.4
P value0.000001
Pvalue mlog6
P value text
Or beta1.24
%95 Ci[NR]
PlatformIllumina [296129]
CNVN
Mapped traitHodgkins lymphoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000183
Study accessionGCST002237