SNP Detail For rs1429411
1.Mapping Information
Human SNP ID rs1429411
Human chromosome chr2
Human SNP position 197279278
Pig chromosome chr15
Pig SNP position 112357145
2.Annotation Information
PubMed ID25338677
JournalGenes Immun
Linkwww.ncbi.nlm.nih.gov/pubmed/25338677
StudyGenetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
Disease/TraitInterferon alpha levels in systemic lupus erythematosus
Initial sample88 European ancestry high interferon alpha cases, 322 European ancestry low interferon alpha cases
Replication sample715 European ancestry cases, 450 African American cases
Region2q33.1
Chromosome idchr2
Chromosome position197279278
Reported geneANKRD44, LOC729342
Mapped geneANKRD44-IT1, ANKRD44
Upstream gene id
Downstream gene id
SNP gene ids101927547, 91526
Upstream gene distance
Downstream gene distance
SNP risk allelers1429411-C
SNPsrs1429411
Merged0
SNP id current1429411
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000005
Pvalue mlog5.30102999566398
P value text(EA)
Or beta1.55
%95 Ci[1.20-2.00]
PlatformIllumina [291943]
CNVN
Mapped traitinterferon alpha measurement, systemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006517, http://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST002666