SNP Detail For rs142850025
1.Mapping Information
Human SNP ID rs142850025
Human chromosome chr11
Human SNP position 42717173
Pig chromosome chr2
Pig SNP position 21135093
2.Annotation Information
PubMed ID24951543
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24951543
StudyMeta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract.
Disease/TraitAge-related nuclear cataracts
Initial sample2,369 Malay ancestry individuals, 2,200 Indian ancestry individuals, 2,571 Chinese ancestry individuals
Replication sampleNA
Region11p12
Chromosome idchr11
Chromosome position42717173
Reported geneintergenic
Mapped geneLOC105376642 - HNRNPKP3
Upstream gene id105376642
Downstream gene id399881
SNP gene ids
Upstream gene distance455242
Downstream gene distance544331
SNP risk allelers142850025-G
SNPsrs142850025
Merged0
SNP id current142850025
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.000006
Pvalue mlog5.22184874961635
P value text(Fixed effect)
Or beta0.19
%95 Ci[0.11-0.27] unit decrease
PlatformIllumina [4736131] (imputed)
CNVN
Mapped traitage-related nuclear cataract
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0011142
Study accessionGCST002498