Human SNP ID | rs1425053 |
---|---|
Human chromosome | chr8 |
Human SNP position | 119200751 |
Pig chromosome | chr4 |
Pig SNP position | 20647472 |
PubMed ID | 25080503 |
---|---|
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25080503 |
Study | Meta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels. |
Disease/Trait | Osteoprotegerin levels |
Initial sample | 4,158 European ancestry males, 531 South Tyrol males, 4,253 European ancestry females, 692 South Tyrol females, 702 Han Chinese ancestry females |
Replication sample | NA |
Region | 8q24.12 |
Chromosome id | chr8 |
Chromosome position | 119200751 |
Reported gene | COLEC10, MAL2, TNFRSF11B |
Mapped gene | LOC105375725 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 105375725 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1425053-A |
SNPs | rs1425053 |
Merged | 0 |
SNP id current | 1425053 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.607 |
P value | 0.000000000000008 |
Pvalue mlog | 14.096910013008 |
P value text | (Sex-combined) |
Or beta | 0.037 |
%95 Ci | [0.028-0.046] unit increase |
Platform | Affymetrix, Illumina [up to 2544063] (imputed) |
CNV | N |
Mapped trait | osteoprotegerin measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005918 |
Study accession | GCST002546 |