SNP Detail For rs1425053
1.Mapping Information
Human SNP ID rs1425053
Human chromosome chr8
Human SNP position 119200751
Pig chromosome chr4
Pig SNP position 20647472
2.Annotation Information
PubMed ID25080503
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25080503
StudyMeta-analysis of genome-wide association studies identifies two loci associated with circulating osteoprotegerin levels.
Disease/TraitOsteoprotegerin levels
Initial sample4,158 European ancestry males, 531 South Tyrol males, 4,253 European ancestry females, 692 South Tyrol females, 702 Han Chinese ancestry females
Replication sampleNA
Region8q24.12
Chromosome idchr8
Chromosome position119200751
Reported geneCOLEC10, MAL2, TNFRSF11B
Mapped geneLOC105375725
Upstream gene id
Downstream gene id
SNP gene ids105375725
Upstream gene distance
Downstream gene distance
SNP risk allelers1425053-A
SNPsrs1425053
Merged0
SNP id current1425053
Contextintron_variant
Intergenic0
Allele frequency0.607
P value0.000000000000008
Pvalue mlog14.096910013008
P value text(Sex-combined)
Or beta0.037
%95 Ci[0.028-0.046] unit increase
PlatformAffymetrix, Illumina [up to 2544063] (imputed)
CNVN
Mapped traitosteoprotegerin measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005918
Study accessionGCST002546