SNP Detail For rs141853578
1.Mapping Information
Human SNP ID rs141853578
Human chromosome chr4
Human SNP position 109764664
Pig chromosome chr8
Pig SNP position 120529658
2.Annotation Information
PubMed ID26691988
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26691988
StudyA large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.
Disease/TraitAdvanced age-related macular degeneration
Initial sample16,144 European ancestry cases, 17,832 European ancestry controls
Replication sample473 Asian ancestry cases, 1,099 Asian ancestry controls, 52 African ancestry cases, 361 African ancestry cases, 254 other non-European ancestry cases, 694 other non-European ancestry controls
Region4q25
Chromosome idchr4
Chromosome position109764664
Reported geneCFI
Mapped geneCFI
Upstream gene id
Downstream gene id
SNP gene ids3426
Upstream gene distance
Downstream gene distance
SNP risk allelers141853578-?
SNPsrs141853578
Merged0
SNP id current141853578
Contextmissense_variant
Intergenic0
Allele frequencyNR
P value0.0000000006
Pvalue mlog9.22184874961635
P value text(EA)
Or beta3.64
%95 Ci
PlatformIllumina [12023830] (imputed)
CNVN
Mapped traitage-related macular degeneration, wet macular degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001365, http://www.ebi.ac.uk/efo/EFO_0004683
Study accessionGCST003219