SNP Detail For rs141644443
1.Mapping Information
Human SNP ID rs141644443
Human chromosome chr4
Human SNP position 147055572
Pig chromosome chr8
Pig SNP position 86822587
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.22
Chromosome idchr4
Chromosome position147055572
Reported geneIntergenic
Mapped geneLOC100996262 - LOC105377476
Upstream gene id100996262
Downstream gene id105377476
SNP gene ids
Upstream gene distance26632
Downstream gene distance15484
SNP risk allelers141644443-G
SNPsrs141644443
Merged0
SNP id current141644443
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.000003
Pvalue mlog5.52287874528033
P value text(AA)
Or beta2.399
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.22
Chromosome idchr4
Chromosome position147055572
Reported geneIntergenic
Mapped geneLOC100996262 - LOC105377476
Upstream gene id100996262
Downstream gene id105377476
SNP gene ids
Upstream gene distance26632
Downstream gene distance15484
SNP risk allelers141644443-G
SNPsrs141644443
Merged0
SNP id current141644443
Contextintergenic_variant
Intergenic1
Allele frequency1
P value0.00000003
Pvalue mlog7.52287874528033
P value text(AA)
Or beta0.559
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264