Human SNP ID | rs1412444 |
---|---|
Human chromosome | chr10 |
Human SNP position | 89243170 |
Pig chromosome | chr14 |
Pig SNP position | 110142348 |
PubMed ID | 21378988 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21378988 |
Study | A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. |
Disease/Trait | Coronary heart disease |
Initial sample | 8,424 European ancestry cases, 7,268 European ancestry controls, 6,996 South Asian ancestry cases, 7,794 South Asian ancestry controls |
Replication sample | 18,049 European ancestry cases, 16,357 European ancestry controls, 3,359 South Asian ancestry cases, 2,828 South Asian ancestry controls |
Region | 10q23.31 |
Chromosome id | chr10 |
Chromosome position | 89243170 |
Reported gene | LIPA |
Mapped gene | LIPA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1412444-T |
SNPs | rs1412444 |
Merged | 0 |
SNP id current | 1412444 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.42 |
P value | 0.0000000000003 |
Pvalue mlog | 12.5228787452803 |
P value text | |
Or beta | 1.09 |
%95 Ci | [1.07-1.12] |
Platform | Illumina [574919] |
CNV | N |
Mapped trait | coronary heart disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001645 |
Study accession | GCST000999 |
PubMed ID | 21606135 |
Journal | Circ Cardiovasc Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21606135 |
Study | A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. |
Disease/Trait | Coronary heart disease |
Initial sample | 2,078 European ancestry cases, 2,953 European ancestry controls |
Replication sample | 19,350 European ancestry cases, 35,408 European ancestry controls |
Region | 10q23.31 |
Chromosome id | chr10 |
Chromosome position | 89243170 |
Reported gene | LIPA |
Mapped gene | LIPA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1412444-T |
SNPs | rs1412444 |
Merged | 0 |
SNP id current | 1412444 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.32 |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | |
Or beta | 1.1 |
%95 Ci | [1.07-1.14] |
Platform | Affymetrix [608247] |
CNV | N |
Mapped trait | coronary heart disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001645 |
Study accession | GCST001079 |
PubMed ID | 26343387 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26343387 |
Study | A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease. |
Disease/Trait | Coronary artery disease |
Initial sample | 42,096 European ancestry cases, 361 African American cases, 758 Hispanic American cases, 12,658 South Asian ancestry cases, 1,802 Lebanese ancestry cases, 3,614 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, |
Replication sample | NA |
Region | 10q23.31 |
Chromosome id | chr10 |
Chromosome position | 89243170 |
Reported gene | LIPA |
Mapped gene | LIPA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3988 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1412444-T |
SNPs | rs1412444 |
Merged | 0 |
SNP id current | 1412444 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.369131 |
P value | 0.000000000005 |
Pvalue mlog | 11.3010299956639 |
P value text | |
Or beta | 1.07 |
%95 Ci | [1.05- 1.09] |
Platform | Affymetrix, Illumina [8600000] (imputed) |
CNV | N |
Mapped trait | coronary artery disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000378 |
Study accession | GCST003116 |