Human SNP ID | rs140522 |
---|---|
Human chromosome | chr22 |
Human SNP position | 50532837 |
Pig chromosome | chr5 |
Pig SNP position | 110564546 |
PubMed ID | 21833088 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/21833088 |
Study | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. |
Disease/Trait | Multiple sclerosis |
Initial sample | 9,772 European ancestry cases, 16,849 European ancestry controls |
Replication sample | 4,218 European ancestry cases, 7,296 European ancestry controls |
Region | 22q13.33 |
Chromosome id | chr22 |
Chromosome position | 50532837 |
Reported gene | ODF3B, SCO2 |
Mapped gene | ODF3B - LOC102724608 |
Upstream gene id | 440836 |
Downstream gene id | 102724608 |
SNP gene ids | |
Upstream gene distance | 258 |
Downstream gene distance | 8577 |
SNP risk allele | rs140522-A |
SNPs | rs140522 |
Merged | 0 |
SNP id current | 140522 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.00000002 |
Pvalue mlog | 7.69897000433601 |
P value text | |
Or beta | 1.1 |
%95 Ci | [1.09-1.12] |
Platform | Illumina [465434] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST001198 |
PubMed ID | 23222517 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/23222517 |
Study | Seventy-five genetic loci influencing the human red blood cell. |
Disease/Trait | Red blood cell traits |
Initial sample | 62,553 European ancestry individuals, 9,308 South Asian ancestry individuals |
Replication sample | 63,506 European ancestry individuals |
Region | 22q13.33 |
Chromosome id | chr22 |
Chromosome position | 50532837 |
Reported gene | TYMP, ODF3B, SCO2, NCAPH2 |
Mapped gene | ODF3B - LOC102724608 |
Upstream gene id | 440836 |
Downstream gene id | 102724608 |
SNP gene ids | |
Upstream gene distance | 258 |
Downstream gene distance | 8577 |
SNP risk allele | rs140522-C |
SNPs | rs140522 |
Merged | 0 |
SNP id current | 140522 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.67 |
P value | 5E-23 |
Pvalue mlog | 22.3010299956639 |
P value text | (EA, MCV) |
Or beta | 0.287 |
%95 Ci | [0.23-0.35] unit increase |
Platform | Affymetrix, Illumina, Perlegen [2711806] (imputed) |
CNV | N |
Mapped trait | mean corpuscular volume |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004526 |
Study accession | GCST001765 |