SNP Detail For rs1385167
1.Mapping Information
Human SNP ID rs1385167
Human chromosome chr2
Human SNP position 65973514
Pig chromosome chr3
Pig SNP position 79798841
2.Annotation Information
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region2p14
Chromosome idchr2
Chromosome position65973514
Reported geneMEIS1
Mapped geneLOC105369168
Upstream gene id
Downstream gene id
SNP gene ids105369168
Upstream gene distance
Downstream gene distance
SNP risk allelers1385167-G
SNPsrs1385167
Merged0
SNP id current1385167
Contextintron_variant
Intergenic0
Allele frequency0.1496
P value0.0000002
Pvalue mlog6.69897000433601
P value text(EA, men)
Or beta0.0363
%95 Ci[0.023-0.05] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region2p14
Chromosome idchr2
Chromosome position65973514
Reported geneMEIS1
Mapped geneLOC105369168
Upstream gene id
Downstream gene id
SNP gene ids105369168
Upstream gene distance
Downstream gene distance
SNP risk allelers1385167-G
SNPsrs1385167
Merged0
SNP id current1385167
Contextintron_variant
Intergenic0
Allele frequency0.1475
P value0.000000002
Pvalue mlog8.69897000433601
P value text(EA)
Or beta0.0293
%95 Ci[0.02-0.039] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region2p14
Chromosome idchr2
Chromosome position65973514
Reported geneMEIS1
Mapped geneLOC105369168
Upstream gene id
Downstream gene id
SNP gene ids105369168
Upstream gene distance
Downstream gene distance
SNP risk allelers1385167-G
SNPsrs1385167
Merged0
SNP id current1385167
Contextintron_variant
Intergenic0
Allele frequency0.1549
P value0.000003
Pvalue mlog5.52287874528033
P value text(men)
Or beta0.0315
%95 Ci[0.018-0.045] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782
PubMed ID25673412
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/25673412
StudyNew genetic loci link adipose and insulin biology to body fat distribution.
Disease/TraitWaist-to-hip ratio adjusted for body mass index
Initial sampleup to 56,910 European ancestry men, up to 86,570 European ancestry women
Replication sampleup to 36,570 European ancestry men, 30,172 European ancestry women, 915 Filipino ancestry men, 735 Filipino ancestry women, 2,351 African-American/Afro-Caribbean ancestry men, 6,258 African-American/Afro-Caribbean ancestry women, 2,285 South Asian ancestr
Region2p14
Chromosome idchr2
Chromosome position65973514
Reported geneMEIS1
Mapped geneLOC105369168
Upstream gene id
Downstream gene id
SNP gene ids105369168
Upstream gene distance
Downstream gene distance
SNP risk allelers1385167-G
SNPsrs1385167
Merged0
SNP id current1385167
Contextintron_variant
Intergenic0
Allele frequency0.1556
P value0.00000001
Pvalue mlog8
P value text
Or beta0.0265
%95 Ci[0.017-0.036] unit increase
PlatformAffymetrix, Illumina, Perlegen [up to 2542447] (imputed)
CNVN
Mapped traitwaist-hip ratio, body mass index
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004343, http://www.ebi.ac.uk/efo/EFO_0004340
Study accessionGCST002782