SNP Detail For rs1381451
1.Mapping Information
Human SNP ID rs1381451
Human chromosome chr16
Human SNP position 51681964
Pig chromosome chr6
Pig SNP position 29828028
2.Annotation Information
PubMed ID21844884
JournalPharmacogenomics J
Linkwww.ncbi.nlm.nih.gov/pubmed/21844884
StudyGenome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
Disease/TraitResponse to platinum-based chemotherapy (carboplatin)
Initial sample176 Sub-Saharan African ancestry lymphoblastoid cell lines, 83 African ancestry lymphoblastoid cell lines, 175 East Asian ancestry lymphoblastoid cell lines, 174 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region16q12.1
Chromosome idchr16
Chromosome position51681964
Reported geneintergenic
Mapped geneHNRNPA1P48 - LOC105371257
Upstream gene id642659
Downstream gene id105371257
SNP gene ids
Upstream gene distance34848
Downstream gene distance37116
SNP risk allelers1381451-?
SNPsrs1381451
Merged0
SNP id current1381451
Contextintergenic_variant
Intergenic1
Allele frequency
P value0.000007
Pvalue mlog5.15490195998574
P value text
Or beta
%95 Ci
PlatformNR [~ 3000000] (imputed)
CNVN
Mapped traitresponse to carboplatin
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328
Study accessionGCST001204