Human SNP ID | rs1351394 |
---|---|
Human chromosome | chr12 |
Human SNP position | 65958046 |
Pig chromosome | chr5 |
Pig SNP position | 33510089 |
PubMed ID | 20881960 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20881960 |
Study | Hundreds of variants clustered in genomic loci and biological pathways affect human height. |
Disease/Trait | Height |
Initial sample | 133,653 European ancestry individuals |
Replication sample | 50,074 European ancestry individuals |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65958046 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8091 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1351394-T |
SNPs | rs1351394 |
Merged | 0 |
SNP id current | 1351394 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 2E-65 |
Pvalue mlog | 64.698970004336 |
P value text | |
Or beta | 0.06 |
%95 Ci | [NR] unit increase |
Platform | Affymetrix, Illumina [2834208] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST000817 |
PubMed ID | 23563607 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Height |
Initial sample | 8,097 European ancestry tall individuals, 8,099 European ancestry short individuals |
Replication sample | 4,872 European ancestry tall individuals, 4,831 European ancestry short individuals |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65958046 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8091 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1351394-T |
SNPs | rs1351394 |
Merged | 0 |
SNP id current | 1351394 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.49 |
P value | 7E-32 |
Pvalue mlog | 31.1549019599857 |
P value text | |
Or beta | 1.26 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | body height |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004339 |
Study accession | GCST001956 |
PubMed ID | 25281659 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25281659 |
Study | A novel common variant in DCST2 is associated with length in early life and height in adulthood. |
Disease/Trait | Birth length |
Initial sample | 28,459 European ancestry individuals |
Replication sample | 16,145 European ancestry individuals, 280 Moroccan ancestry individuals, 284 Surinamese ancestry individuals, 319 Turkish ancestry individuals, 651 Chinese ancestry individuals |
Region | 12q14.3 |
Chromosome id | chr12 |
Chromosome position | 65958046 |
Reported gene | HMGA2 |
Mapped gene | HMGA2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8091 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs1351394-T |
SNPs | rs1351394 |
Merged | 0 |
SNP id current | 1351394 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.498 |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | |
Or beta | 0.044 |
%95 Ci | [0.026-0.062] unit increase |
Platform | Affymetrix, Illumina [2201971] (imputed) |
CNV | N |
Mapped trait | body height at birth |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006784 |
Study accession | GCST002644 |