SNP Detail For rs1346751
1.Mapping Information
Human SNP ID rs1346751
Human chromosome chr2
Human SNP position 16458298
Pig chromosome chr3
Pig SNP position 129397538
2.Annotation Information
PubMed ID24554482
JournalJ Neurovirol
Linkwww.ncbi.nlm.nih.gov/pubmed/24554482
StudyGenome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Disease/TraitResponse to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy)
Initial sample19 European ancestry cases, 30 African American cases, 9 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls
Replication sampleNA
Region2p24.3
Chromosome idchr2
Chromosome position16458298
Reported geneFAM49A
Mapped geneLOC105373444
Upstream gene id
Downstream gene id
SNP gene ids105373444
Upstream gene distance
Downstream gene distance
SNP risk allelers1346751-?
SNPsrs1346751
Merged0
SNP id current1346751
Contextintergenic_variant
Intergenic0
Allele frequency
P value0.000008
Pvalue mlog5.09691001300805
P value text(AA)
Or beta0.1
%95 Ci[NR]
PlatformIllumina [936149]
CNVN
Mapped traitresponse to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100
Study accessionGCST002365