Human SNP ID | rs1344653 |
---|---|
Human chromosome | chr2 |
Human SNP position | 19531084 |
Pig chromosome | chr3 |
Pig SNP position | 126680693 |
PubMed ID | 26390057 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26390057 |
Study | Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. |
Disease/Trait | Pulse pressure |
Initial sample | 31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals |
Replication sample | 87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals |
Region | 2p24.1 |
Chromosome id | chr2 |
Chromosome position | 19531084 |
Reported gene | OSR1 |
Mapped gene | LOC105373460 - LOC105373459 |
Upstream gene id | 105373460 |
Downstream gene id | 105373459 |
SNP gene ids | |
Upstream gene distance | 11074 |
Downstream gene distance | 59180 |
SNP risk allele | rs1344653-A |
SNPs | rs1344653 |
Merged | |
SNP id current | 1344653 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.530994775663925 |
P value | 0.000000000008 |
Pvalue mlog | 11.096910013008 |
P value text | |
Or beta | 0.26579088 |
%95 Ci | [0.19-0.34] mmHg decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2100000] (imputed) |
CNV | N |
Mapped trait | pulse pressure measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005763 |
Study accession | GCST003274 |