SNP Detail For rs1344555
1.Mapping Information
Human SNP ID rs1344555
Human chromosome chr3
Human SNP position 169582431
Pig chromosome chr13
Pig SNP position 117015835
2.Annotation Information
PubMed ID21946350
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21946350
StudyGenome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
Disease/TraitPulmonary function
Initial sample48,201 European ancestry individuals
Replication sample46,411 European ancestry individuals
Region3q26.2
Chromosome idchr3
Chromosome position169582431
Reported geneMECOM
Mapped geneMECOM
Upstream gene id
Downstream gene id
SNP gene ids2122
Upstream gene distance
Downstream gene distance
SNP risk allelers1344555-T
SNPsrs1344555
Merged0
SNP id current1344555
Contextintron_variant
Intergenic0
Allele frequency0.21
P value0.00000003
Pvalue mlog7.52287874528033
P value text(FEV1)
Or beta0.034
%95 Ci[0.022-0.046] unit decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitpulmonary function measurement, forced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003892, http://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001251
PubMed ID23284291
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23284291
StudyGenome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Disease/TraitPulmonary function (interaction)
Initial sample50,047 European ancestry individuals
Replication sampleNA
Region3q26.2
Chromosome idchr3
Chromosome position169582431
Reported geneMECOM
Mapped geneMECOM
Upstream gene id
Downstream gene id
SNP gene ids2122
Upstream gene distance
Downstream gene distance
SNP risk allelers1344555-?
SNPsrs1344555
Merged0
SNP id current1344555
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000004
Pvalue mlog5.39794000867203
P value text(FEV1, Pack-years)
Or beta
%95 Ci
PlatformNR [~ 2500000] (imputed)
CNVN
Mapped traitforced expiratory volume
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314
Study accessionGCST001784