Human SNP ID | rs1343151 |
---|---|
Human chromosome | chr1 |
Human SNP position | 67253446 |
Pig chromosome | chr6 |
Pig SNP position | 134226769 |
PubMed ID | 17804789 |
---|---|
Journal | Proc Natl Acad Sci U S A |
Link | www.ncbi.nlm.nih.gov/pubmed/17804789 |
Study | Genome-wide association study for Crohn__s disease in the Quebec Founder Population identifies multiple validated disease loci. |
Disease/Trait | Crohn__s disease |
Initial sample | 382 French Canadian founder trios |
Replication sample | 750 European ancestry cases, 828 European ancestry controls, 521 European ancestry trios |
Region | 1p31.3 |
Chromosome id | chr1;1;1;1;1;1;1;1;1;1;1;1;1;1;1;1 |
Chromosome position | 67264945;67240275;67253446;67264372;67256884;67135449;67262335;67124778;67236843;67259437;67228519;67204530;67260421;67205233;67187327;67219915 |
Reported gene | IL23R |
Mapped gene | IL23R - LOC100130497; IL23R; IL23R; IL23R - LOC100130497; IL23R; C1orf141; IL23R - LOC100130497; C1orf141; IL23R; IL23R; IL23R; IL23R; IL23R - RNU4ATAC4P; IL23R; IL23R; IL23R |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10789230-?; rs11209026-?; rs1343151-?; rs6669582-?; rs10889676-?; rs11209003-?; rs12567232-?; rs11209002-?; rs11465804-?; rs10889677-?; rs2201841-?; rs1004819-?; rs9988642-?; rs2902440-?; rs2064689-?; rs11465802-? |
SNPs | rs10789230; rs11209026; rs1343151; rs6669582; rs10889676; rs11209003; rs12567232; rs11209002; rs11465804; rs10889677; rs2201841; rs1004819; rs9988642; rs2902440; rs2064689; rs11465802 |
Merged | 0 |
SNP id current | |
Context | downstream_gene_variant; missense_variant; intron_variant; downstream_gene_variant; intron_variant; intron_variant; downstream_gene_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant; downstream_gene_variant; intr |
Intergenic | |
Allele frequency | 0.23 |
P value | 0.00000001 |
Pvalue mlog | 8 |
P value text | |
Or beta | 1.38 |
%95 Ci | [1.23-1.53] |
Platform | Perlegen [164279] |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST000071 |
PubMed ID | 17804789 |
Journal | Proc Natl Acad Sci U S A |
Link | www.ncbi.nlm.nih.gov/pubmed/17804789 |
Study | Genome-wide association study for Crohn__s disease in the Quebec Founder Population identifies multiple validated disease loci. |
Disease/Trait | Crohn__s disease |
Initial sample | 382 French Canadian founder trios |
Replication sample | 750 European ancestry cases, 828 European ancestry controls, 521 European ancestry trios |
Region | 1p31.3 |
Chromosome id | chr1;1;1;1;1;1;1;1;1;1;1;1;1;1;1;1 |
Chromosome position | 67264945;67240275;67253446;67264372;67256884;67135449;67262335;67124778;67236843;67259437;67228519;67204530;67260421;67205233;67187327;67219915 |
Reported gene | IL23R |
Mapped gene | IL23R - LOC100130497; IL23R; IL23R; IL23R - LOC100130497; IL23R; C1orf141; IL23R - LOC100130497; C1orf141; IL23R; IL23R; IL23R; IL23R; IL23R - RNU4ATAC4P; IL23R; IL23R; IL23R |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs10789230-?; rs11209026-?; rs1343151-?; rs6669582-?; rs10889676-?; rs11209003-?; rs12567232-?; rs11209002-?; rs11465804-?; rs10889677-?; rs2201841-?; rs1004819-?; rs9988642-?; rs2902440-?; rs2064689-?; rs11465802-? |
SNPs | rs10789230; rs11209026; rs1343151; rs6669582; rs10889676; rs11209003; rs12567232; rs11209002; rs11465804; rs10889677; rs2201841; rs1004819; rs9988642; rs2902440; rs2064689; rs11465802 |
Merged | 0 |
SNP id current | |
Context | downstream_gene_variant; missense_variant; intron_variant; downstream_gene_variant; intron_variant; intron_variant; downstream_gene_variant; intron_variant; intron_variant; 3_prime_UTR_variant; intron_variant; intron_variant; downstream_gene_variant; intr |
Intergenic | |
Allele frequency | 0.97 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | |
Or beta | 2.56 |
%95 Ci | [1.75-3.70] |
Platform | Perlegen [164279] |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST000071 |