SNP Detail For rs13429458
1.Mapping Information
Human SNP ID rs13429458
Human chromosome chr2
Human SNP position 43411699
Pig chromosome chr3
Pig SNP position 103042332
2.Annotation Information
PubMed ID21151128
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21151128
StudyGenome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.
Disease/TraitPolycystic ovary syndrome
Initial sample744 Han Chinese ancestry cases, 895 Han Chinese ancestry controls
Replication sample3,338 Han Chinese ancestry cases, 5,792 Han Chinese ancestry controls
Region2p21
Chromosome idchr2
Chromosome position43411699
Reported geneZFP36L2, LOC100129726, THADA
Mapped geneTHADA
Upstream gene id
Downstream gene id
SNP gene ids63892
Upstream gene distance
Downstream gene distance
SNP risk allelers13429458-A
SNPsrs13429458
Merged0
SNP id current13429458
Contextintron_variant
Intergenic0
Allele frequency0.91
P value2E-23
Pvalue mlog22.698970004336
P value text
Or beta1.49
%95 Ci[1.39-1.61]
PlatformAffymetrix [611633]
CNVN
Mapped traitpolycystic ovary syndrome
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000660
Study accessionGCST000914
PubMed ID22885925
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/22885925
StudyGenome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
Disease/TraitPolycystic ovary syndrome
Initial sample2,254 Han Chinese ancestry cases, 3,001 Han Chinese ancestry controls
Replication sample8,226 Han Chinese ancestry cases, 7,578 Han Chinese ancestry controls
Region2p21
Chromosome idchr2
Chromosome position43411699
Reported geneNR
Mapped geneTHADA
Upstream gene id
Downstream gene id
SNP gene ids63892
Upstream gene distance
Downstream gene distance
SNP risk allelers13429458-A
SNPsrs13429458
Merged0
SNP id current13429458
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000000004
Pvalue mlog12.397940008672
P value text
Or beta1.49
%95 Ci[NR]
PlatformAffymetrix [NR] (imputed)
CNVN
Mapped traitpolycystic ovary syndrome
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000660
Study accessionGCST001634
PubMed ID22952603
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/22952603
StudyGenome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
Disease/TraitResponse to amphetamines
Initial sample1 American Indian ancestry individual, 18 African American individuals, 10 Asian ancestry individuals, 325 European ancestry individuals, 17 Hispanic individuals, 10 individuals
Replication sampleNA
Region2p21
Chromosome idchr2
Chromosome position43411699
Reported geneTHADA
Mapped geneTHADA
Upstream gene id
Downstream gene id
SNP gene ids63892
Upstream gene distance
Downstream gene distance
SNP risk allelers13429458-?
SNPsrs13429458
Merged0
SNP id current13429458
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000006
Pvalue mlog5.22184874961635
P value text(SF4)
Or beta
%95 Ci
PlatformAffymetrix [5476100] (imputed)
CNVN
Mapped traitresponse to drug
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0042493
Study accessionGCST001651