Human SNP ID | rs13397985 |
---|---|
Human chromosome | chr2 |
Human SNP position | 230226508 |
Pig chromosome | chr15 |
Pig SNP position | 144912599 |
PubMed ID | 18758461 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/18758461 |
Study | A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. |
Disease/Trait | Chronic lymphocytic leukemia |
Initial sample | 505 European ancestry cases, 1,438 European ancestry controls |
Replication sample | 1,024 European ancestry cases, 1,677 European ancestry controls |
Region | 2q37.1 |
Chromosome id | chr2 |
Chromosome position | 230226508 |
Reported gene | SP140, SP110 |
Mapped gene | SP140 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 11262 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13397985-G |
SNPs | rs13397985 |
Merged | 0 |
SNP id current | 13397985 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.0000000006 |
Pvalue mlog | 9.22184874961635 |
P value text | |
Or beta | 1.41 |
%95 Ci | [1.26-1.57] |
Platform | Illumina [345665] |
CNV | N |
Mapped trait | chronic lymphocytic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000095 |
Study accession | GCST000224 |
PubMed ID | 22700719 |
Journal | Blood |
Link | www.ncbi.nlm.nih.gov/pubmed/22700719 |
Study | Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. |
Disease/Trait | Chronic lymphocytic leukemia |
Initial sample | 1,121 European ancestry cases, 3,745 European ancestry controls |
Replication sample | 861 European ancestry cases, 2,033 European ancestry controls |
Region | 2q37.1 |
Chromosome id | chr2 |
Chromosome position | 230226508 |
Reported gene | NR |
Mapped gene | SP140 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 11262 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13397985-? |
SNPs | rs13397985 |
Merged | 0 |
SNP id current | 13397985 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.81 |
P value | 0.0000002 |
Pvalue mlog | 6.69897000433601 |
P value text | |
Or beta | 1.39 |
%95 Ci | [1.23-1.59] |
Platform | Affymetrix, Illumina [~ 1500000] (imputed) |
CNV | N |
Mapped trait | chronic lymphocytic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000095 |
Study accession | GCST001570 |
PubMed ID | 23770605 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23770605 |
Study | Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. |
Disease/Trait | Chronic lymphocytic leukemia |
Initial sample | 2,179 European ancestry cases, 6,221 European ancestry controls |
Replication sample | 1,709 European ancestry cases, 6,318 European ancestry controls |
Region | 2q37.1 |
Chromosome id | chr2 |
Chromosome position | 230226508 |
Reported gene | SP140 |
Mapped gene | SP140 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 11262 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13397985-G |
SNPs | rs13397985 |
Merged | 0 |
SNP id current | 13397985 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.18 |
P value | 1E-22 |
Pvalue mlog | 22 |
P value text | |
Or beta | 1.45 |
%95 Ci | [NR] |
Platform | Illumina [549934] |
CNV | N |
Mapped trait | chronic lymphocytic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000095 |
Study accession | GCST002073 |
PubMed ID | 24292274 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24292274 |
Study | A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. |
Disease/Trait | Chronic lymphocytic leukemia |
Initial sample | 1,739 European ancestry cases, 5,199 European ancestry controls |
Replication sample | 1,144 European ancestry cases, 3,151 European ancestry controls |
Region | 2q37.1 |
Chromosome id | chr2 |
Chromosome position | 230226508 |
Reported gene | SP140, SP110 |
Mapped gene | SP140 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 11262 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13397985-G |
SNPs | rs13397985 |
Merged | 0 |
SNP id current | 13397985 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.19 |
P value | 0.0000000000005 |
Pvalue mlog | 12.3010299956639 |
P value text | |
Or beta | 1.43 |
%95 Ci | [NR] |
Platform | Illumina [450000] (imputed) |
CNV | N |
Mapped trait | chronic lymphocytic leukemia |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000095 |
Study accession | GCST002299 |