SNP Detail For rs1335532
1.Mapping Information
Human SNP ID rs1335532
Human chromosome chr1
Human SNP position 116558335
Pig chromosome chr4
Pig SNP position 114187789
2.Annotation Information
PubMed ID19525955
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19525955
StudyGenome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.
Disease/TraitMultiple sclerosis
Initial sample1,618 European ancestry cases, 3,413 European ancestry controls
Replication sample2,256 European ancestry cases, 2,310 European ancestry controls
Region1p13.1
Chromosome idchr1
Chromosome position116558335
Reported geneCD58
Mapped geneCD58
Upstream gene id
Downstream gene id
SNP gene ids965
Upstream gene distance
Downstream gene distance
SNP risk allelers1335532-A
SNPsrs1335532
Merged0
SNP id current1335532
Contextintron_variant
Intergenic0
Allele frequency0.87
P value0.0000001
Pvalue mlog7
P value text
Or beta1.28
%95 Ci[NR]
PlatformIllumina [302098]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST000425
PubMed ID21833088
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21833088
StudyGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Disease/TraitMultiple sclerosis
Initial sample9,772 European ancestry cases, 16,849 European ancestry controls
Replication sample4,218 European ancestry cases, 7,296 European ancestry controls
Region1p13.1
Chromosome idchr1
Chromosome position116558335
Reported geneCD58
Mapped geneCD58
Upstream gene id
Downstream gene id
SNP gene ids965
Upstream gene distance
Downstream gene distance
SNP risk allelers1335532-A
SNPsrs1335532
Merged0
SNP id current1335532
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000000000003
Pvalue mlog15.5228787452803
P value text
Or beta1.22
%95 Ci[1.19-1.24]
PlatformIllumina [465434]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001198