Human SNP ID | rs1332099 |
---|---|
Human chromosome | chr10 |
Human SNP position | 99538694 |
Pig chromosome | chr14 |
Pig SNP position | 120172025 |
PubMed ID | 26301688 |
---|---|
Journal | Nat Med |
Link | www.ncbi.nlm.nih.gov/pubmed/26301688 |
Study | Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. |
Disease/Trait | Pediatric autoimmune diseases |
Initial sample | 97 European ancestry thyroiditis cases, 107 European ancestry ankylosing spondylitis cases, 100 European ancestry psoriasis cases, 173 European ancestry celiac disease cases, 254 European ancestry systemic lupus erythematosus cases, 308 European ancestry |
Replication sample | NA |
Region | 10q24.2 |
Chromosome id | chr10 |
Chromosome position | 99538694 |
Reported gene | NKX2-3 |
Mapped gene | NKX2-3 - SLC25A28 |
Upstream gene id | 159296 |
Downstream gene id | 81894 |
SNP gene ids | |
Upstream gene distance | 2170 |
Downstream gene distance | 71824 |
SNP risk allele | rs1332099-T |
SNPs | rs1332099 |
Merged | |
SNP id current | 1332099 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.46 |
P value | 0.00000000009 |
Pvalue mlog | 10.0457574905606 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [7347414] (imputed) |
CNV | N |
Mapped trait | autoimmune thyroid disease, type I diabetes mellitus, Common variable immunodeficiency, chronic childhood arthritis, ankylosing spondylitis, psoriasis, celiac disease, ulcerative colitis, Crohn__s disease, autoimmune disease, systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0006812, http://www.ebi.ac.uk/efo/EFO_0001359, http://www.orpha.net/ORDO/Orphanet_1572, http://www.ebi.ac.uk/efo/EFO_0002609, http://www.ebi.ac.uk/efo/EFO_0003898, http://www.ebi.ac.uk/efo/EFO_0000676, http://www.ebi.ac.uk/efo |
Study accession | GCST003097 |