Human SNP ID | rs1329568 |
---|---|
Human chromosome | chr9 |
Human SNP position | 37037979 |
Pig chromosome | chr1 |
Pig SNP position | 265638882 |
PubMed ID | 22491018 |
---|---|
Journal | Pharmacogenomics J |
Link | www.ncbi.nlm.nih.gov/pubmed/22491018 |
Study | Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. |
Disease/Trait | Response to tocilizumab in rheumatoid arthritis |
Initial sample | 1,157 European and other ancestry rheumatoid arthritis cases |
Replication sample | 526 European and other ancestry rheumatoid arthritis cases |
Region | 9p13.2 |
Chromosome id | chr9 |
Chromosome position | 37037979 |
Reported gene | intergenic |
Mapped gene | PAX5 - EBLN3 |
Upstream gene id | 5079 |
Downstream gene id | 100506710 |
SNP gene ids | |
Upstream gene distance | 2660 |
Downstream gene distance | 41917 |
SNP risk allele | rs1329568-? |
SNPs | rs1329568 |
Merged | 0 |
SNP id current | 1329568 |
Context | upstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.029 |
P value | 0.0000008 |
Pvalue mlog | 6.09691001300805 |
P value text | (CSJC, RF-) |
Or beta | 19.64 |
%95 Ci | [NR] unit increase |
Platform | Illumina [534053] |
CNV | N |
Mapped trait | rheumatoid arthritis, response to drug |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685, http://purl.obolibrary.org/obo/GO_0042493 |
Study accession | GCST001476 |
PubMed ID | 25786224 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/25786224 |
Study | Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study. |
Disease/Trait | HIV-1 susceptibility |
Initial sample | 628 African American high risk-cases, 1,376 African American high-risk controls, 327 European ancestry high-risk cases, 805 European ancestry high-risk controls |
Replication sample | 1,395 African American high-risk cases, 457 African American high-risk controls, 513 European ancestry high-risk cases, 168 European ancestry high-risk controls |
Region | 9p13.2 |
Chromosome id | chr9;9 |
Chromosome position | 37654260;37037979 |
Reported gene | FRMPD1 |
Mapped gene | FRMPD1; PAX5 - EBLN3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4878712-A; rs1329568-T |
SNPs | rs4878712; rs1329568 |
Merged | 0 |
SNP id current | |
Context | intron_variant; upstream_gene_variant |
Intergenic | |
Allele frequency | |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | (AA) |
Or beta | 1.64 |
%95 Ci | [1.32-2.00] |
Platform | Illumina [~ 8000000] (imputed) |
CNV | N |
Mapped trait | HIV-1 infection, Susceptibility to viral and mycobacterial infections |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000180, http://www.orpha.net/ORDO/Orphanet_391311 |
Study accession | GCST002818 |
PubMed ID | 25786224 |
Journal | PLoS One |
Link | www.ncbi.nlm.nih.gov/pubmed/25786224 |
Study | Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study. |
Disease/Trait | HIV-1 susceptibility |
Initial sample | 628 African American high risk-cases, 1,376 African American high-risk controls, 327 European ancestry high-risk cases, 805 European ancestry high-risk controls |
Replication sample | 1,395 African American high-risk cases, 457 African American high-risk controls, 513 European ancestry high-risk cases, 168 European ancestry high-risk controls |
Region | 9p13.2 |
Chromosome id | chr9;9 |
Chromosome position | 37654260;37037979 |
Reported gene | FRMPD1 |
Mapped gene | FRMPD1; PAX5 - EBLN3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4878712-A; rs1329568-T |
SNPs | rs4878712; rs1329568 |
Merged | 0 |
SNP id current | |
Context | intron_variant; upstream_gene_variant |
Intergenic | |
Allele frequency | |
P value | 0.00000005 |
Pvalue mlog | 7.30102999566398 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [~ 8000000] (imputed) |
CNV | N |
Mapped trait | HIV-1 infection, Susceptibility to viral and mycobacterial infections |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000180, http://www.orpha.net/ORDO/Orphanet_391311 |
Study accession | GCST002818 |