SNP Detail For rs13272623
1.Mapping Information
Human SNP ID rs13272623
Human chromosome chr8
Human SNP position 70632513
Pig chromosome chr4
Pig SNP position 70385589
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q13.3
Chromosome idchr8
Chromosome position70632513
Reported geneNR
Mapped geneLOC286190
Upstream gene id
Downstream gene id
SNP gene ids286190
Upstream gene distance
Downstream gene distance
SNP risk allelers13272623-G
SNPsrs13272623
Merged0
SNP id current13272623
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.154915348909657
P value0.000002
Pvalue mlog5.69897000433601
P value text(IGP47)
Or beta0.218
%95 Ci[0.13-0.31] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q13.3
Chromosome idchr8
Chromosome position70632513
Reported geneNR
Mapped geneLOC286190
Upstream gene id
Downstream gene id
SNP gene ids286190
Upstream gene distance
Downstream gene distance
SNP risk allelers13272623-G
SNPsrs13272623
Merged0
SNP id current13272623
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.155110978134761
P value0.000004
Pvalue mlog5.39794000867203
P value text(IGP56)
Or beta0.2093
%95 Ci[0.12-0.3] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region8q13.3
Chromosome idchr8
Chromosome position70632513
Reported geneNR
Mapped geneLOC286190
Upstream gene id
Downstream gene id
SNP gene ids286190
Upstream gene distance
Downstream gene distance
SNP risk allelers13272623-G
SNPsrs13272623
Merged0
SNP id current13272623
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.154915348909657
P value0.000002
Pvalue mlog5.69897000433601
P value text(IGP7)
Or beta0.2155
%95 Ci[0.13-0.3] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848