Human SNP ID | rs13272623 |
---|---|
Human chromosome | chr8 |
Human SNP position | 70632513 |
Pig chromosome | chr4 |
Pig SNP position | 70385589 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 8q13.3 |
Chromosome id | chr8 |
Chromosome position | 70632513 |
Reported gene | NR |
Mapped gene | LOC286190 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 286190 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13272623-G |
SNPs | rs13272623 |
Merged | 0 |
SNP id current | 13272623 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.154915348909657 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP47) |
Or beta | 0.218 |
%95 Ci | [0.13-0.31] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 8q13.3 |
Chromosome id | chr8 |
Chromosome position | 70632513 |
Reported gene | NR |
Mapped gene | LOC286190 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 286190 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13272623-G |
SNPs | rs13272623 |
Merged | 0 |
SNP id current | 13272623 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.155110978134761 |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (IGP56) |
Or beta | 0.2093 |
%95 Ci | [0.12-0.3] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 8q13.3 |
Chromosome id | chr8 |
Chromosome position | 70632513 |
Reported gene | NR |
Mapped gene | LOC286190 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 286190 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13272623-G |
SNPs | rs13272623 |
Merged | 0 |
SNP id current | 13272623 |
Context | non_coding_transcript_exon_variant |
Intergenic | 0 |
Allele frequency | 0.154915348909657 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP7) |
Or beta | 0.2155 |
%95 Ci | [0.13-0.3] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |