SNP Detail For rs1318653
1.Mapping Information
Human SNP ID rs1318653
Human chromosome chr1
Human SNP position 207841577
Pig chromosome chr9
Pig SNP position 148494672
2.Annotation Information
PubMed ID25344690
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25344690
StudyCommon variants associated with general and MMR vaccine-related febrile seizures.
Disease/TraitFebrile seizures
Initial sample929 European ancestry MMR vaccine-related febrile seizures cases, 1,070 European ancestry MMR vaccine-unrelated febrile seizures cases, 4,118 European ancestry controls
Replication sampleUp to 408 European ancestry MMR vaccine-related febrile seizures cases, Up to 1,034 European ancestry MMR vaccine-unrelated febrile seizures cases, Up to 1,645 European ancestry controls
Region1q32.2
Chromosome idchr1
Chromosome position207841577
Reported geneintergenic
Mapped geneC1orf132
Upstream gene id
Downstream gene id
SNP gene ids100128537
Upstream gene distance
Downstream gene distance
SNP risk allelers1318653-T
SNPsrs1318653
Merged0
SNP id current1318653
Contextintron_variant
Intergenic0
Allele frequency0.771
P value0.000000002
Pvalue mlog8.69897000433601
P value text(MMR-related vs MMR-unrelated)
Or beta1.48
%95 Ci[1.30-1.67]
PlatformIllumina [up to 8129553] (imputed)
CNVN
Mapped traitfebrile seizures, MMR-related febrile seizures
Mapped trait URIhttp://purl.obolibrary.org/obo/HP_0002373, http://www.ebi.ac.uk/efo/EFO_0006519
Study accessionGCST002672
PubMed ID25344690
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25344690
StudyCommon variants associated with general and MMR vaccine-related febrile seizures.
Disease/TraitFebrile seizures (MMR vaccine-related)
Initial sample929 European ancestry cases, 4,118 European ancestry controls
Replication sampleUp to 408 European ancestry cases, Up to 1,645 European ancestry controls
Region1q32.2
Chromosome idchr1
Chromosome position207841577
Reported geneCD46, CD34
Mapped geneC1orf132
Upstream gene id
Downstream gene id
SNP gene ids100128537
Upstream gene distance
Downstream gene distance
SNP risk allelers1318653-T
SNPsrs1318653
Merged0
SNP id current1318653
Contextintron_variant
Intergenic0
Allele frequency0.774
P value0.0000000001
Pvalue mlog10
P value text
Or beta1.43
%95 Ci[1.28-1.59]
PlatformIllumina [8129524] (imputed)
CNVN
Mapped traitMMR-related febrile seizures
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006519
Study accessionGCST002674