PigVar

1.Mapping Information

Human SNP ID	rs13149993
Human chromosome	chr4
Human SNP position	80237391
Pig chromosome	chr8
Pig SNP position	146726808

2.Annotation Information

PubMed ID	26390057
Journal	Nat Genet
Link	www.ncbi.nlm.nih.gov/pubmed/26390057
Study	Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Disease/Trait	Mean arterial pressure
Initial sample	31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals
Replication sample	87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals
Region	4q21.21
Chromosome id	chr4
Chromosome position	80237391
Reported gene	FGF5
Mapped gene	LOC105377304
Upstream gene id
Downstream gene id
SNP gene ids	105377304
Upstream gene distance
Downstream gene distance
SNP risk allele	rs13149993-A
SNPs	rs13149993
Merged
SNP id current	13149993
Context	intergenic_variant
Intergenic	0
Allele frequency	0.3421
P value	0.00000000000000002
Pvalue mlog	16.698970004336
P value text
Or beta	0.5673
%95 Ci	[0.44-0.7] mmHg increase
Platform	Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)
CNV	N
Mapped trait	mean arterial pressure
Mapped trait URI	http://www.ebi.ac.uk/efo/EFO_0006340
Study accession	GCST003275

PubMed ID	26390057
Journal	Nat Genet
Link	www.ncbi.nlm.nih.gov/pubmed/26390057
Study	Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Disease/Trait	Mean arterial pressure
Initial sample	31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals
Replication sample	87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals
Region	4q21.21
Chromosome id	chr4
Chromosome position	80237391
Reported gene	FGF5
Mapped gene	LOC105377304
Upstream gene id
Downstream gene id
SNP gene ids	105377304
Upstream gene distance
Downstream gene distance
SNP risk allele	rs13149993-A
SNPs	rs13149993
Merged
SNP id current	13149993
Context	intergenic_variant
Intergenic	0
Allele frequency	0.4038
P value	0.000000000009
Pvalue mlog	11.0457574905606
P value text	(East Asians)
Or beta	0.7718
%95 Ci	[0.55-0.99] mmHg increase
Platform	Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)
CNV	N
Mapped trait	mean arterial pressure
Mapped trait URI	http://www.ebi.ac.uk/efo/EFO_0006340
Study accession	GCST003275

PubMed ID	26390057
Journal	Nat Genet
Link	www.ncbi.nlm.nih.gov/pubmed/26390057
Study	Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Disease/Trait	Mean arterial pressure
Initial sample	31,516 East Asian ancestry individuals, 35,352 European ancestry individuals, 33,126 South Asian ancestry individuals
Replication sample	87,205 individuals, 48,268 East Asian ancestry individuals, 68,456 European ancestry individuals and 16,328 South Asian ancestry individuals
Region	4q21.21
Chromosome id	chr4
Chromosome position	80237391
Reported gene	FGF5
Mapped gene	LOC105377304
Upstream gene id
Downstream gene id
SNP gene ids	105377304
Upstream gene distance
Downstream gene distance
SNP risk allele	rs13149993-A
SNPs	rs13149993
Merged
SNP id current	13149993
Context	intergenic_variant
Intergenic	0
Allele frequency	0.2838
P value	0.0000001
Pvalue mlog	7
P value text	(South Asians)
Or beta	0.6454
%95 Ci	[0.41-0.89] mmHg increase
Platform	Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)
CNV	N
Mapped trait	mean arterial pressure
Mapped trait URI	http://www.ebi.ac.uk/efo/EFO_0006340
Study accession	GCST003275

THE PIG VARIATIONS AND POSITIVE SELECTION DATABASE