Human SNP ID | rs13146355 |
---|---|
Human chromosome | chr4 |
Human SNP position | 76490987 |
Pig chromosome | chr8 |
Pig SNP position | 76348436 |
PubMed ID | 20700443 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/20700443 |
Study | Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels. |
Disease/Trait | Magnesium levels |
Initial sample | 15,366 European ancestry individuals |
Replication sample | 8,463 European ancestry individuals |
Region | 4q21.1 |
Chromosome id | chr4 |
Chromosome position | 76490987 |
Reported gene | SHROOM3 |
Mapped gene | SHROOM3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57619 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13146355-G |
SNPs | rs13146355 |
Merged | 0 |
SNP id current | 13146355 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.56 |
P value | 0.0000000000006 |
Pvalue mlog | 12.2218487496163 |
P value text | |
Or beta | 0.01 |
%95 Ci | [0.003-0.007] mmol/L decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | magnesium measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004845 |
Study accession | GCST000756 |
PubMed ID | 22797727 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22797727 |
Study | Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Disease/Trait | Renal function-related traits (sCR) |
Initial sample | 42,257 East Asian, South Asian, and South East Asian ancestry individuals |
Replication sample | 19,662 East Asian ancestry individuals |
Region | 4q21.1 |
Chromosome id | chr4 |
Chromosome position | 76490987 |
Reported gene | SHROOM3 |
Mapped gene | SHROOM3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57619 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13146355-A |
SNPs | rs13146355 |
Merged | 0 |
SNP id current | 13146355 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.21 |
P value | 0.000000000009 |
Pvalue mlog | 11.0457574905606 |
P value text | |
Or beta | 0.0047 |
%95 Ci | [0.0033-0.0061] mg/dl increase |
Platform | Affymetrix, Illumina [2353587] (imputed) |
CNV | N |
Mapped trait | renal system measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742 |
Study accession | GCST001606 |
PubMed ID | 22797727 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22797727 |
Study | Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. |
Disease/Trait | Renal function-related traits (eGRFcrea) |
Initial sample | 42,451 East Asian, South Asian, and South East Asian ancestry individuals |
Replication sample | 19,636 East Asian ancestry individuals |
Region | 4q21.1 |
Chromosome id | chr4 |
Chromosome position | 76490987 |
Reported gene | SHROOM3 |
Mapped gene | SHROOM3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 57619 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs13146355-A |
SNPs | rs13146355 |
Merged | 0 |
SNP id current | 13146355 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.21 |
P value | 0.00000000007 |
Pvalue mlog | 10.1549019599857 |
P value text | |
Or beta | 0.0051 |
%95 Ci | [0.0035-0.0067] ml/min/1.73m2 decrease |
Platform | Affymetrix, Illumina [2353587] (imputed) |
CNV | N |
Mapped trait | renal system measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004742 |
Study accession | GCST001607 |