Human SNP ID | rs13130484 |
---|---|
Human chromosome | chr4 |
Human SNP position | 45173674 |
Pig chromosome | chr8 |
Pig SNP position | 37334405 |
PubMed ID | 23563607 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Obesity |
Initial sample | 93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls |
Replication sample | 65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls |
Region | 4p12 |
Chromosome id | chr4 |
Chromosome position | 45173674 |
Reported gene | GNPDA2 |
Mapped gene | LOC105374441 - PRKRIRP9 |
Upstream gene id | 105374441 |
Downstream gene id | 100131309 |
SNP gene ids | |
Upstream gene distance | 249087 |
Downstream gene distance | 150071 |
SNP risk allele | rs13130484-T |
SNPs | rs13130484 |
Merged | 0 |
SNP id current | 13130484 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.43 |
P value | 4E-28 |
Pvalue mlog | 27.397940008672 |
P value text | (Overweight) |
Or beta | 1.08 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST001953 |
PubMed ID | 23669352 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23669352 |
Study | Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. |
Disease/Trait | Body mass index |
Initial sample | Up to 13,627 European ancestry individuals |
Replication sample | Up to 16,253 European ancestry individuals |
Region | 4p12 |
Chromosome id | chr4 |
Chromosome position | 45173674 |
Reported gene | GNPDA2 |
Mapped gene | LOC105374441 - PRKRIRP9 |
Upstream gene id | 105374441 |
Downstream gene id | 100131309 |
SNP gene ids | |
Upstream gene distance | 249087 |
Downstream gene distance | 150071 |
SNP risk allele | rs13130484-T |
SNPs | rs13130484 |
Merged | 0 |
SNP id current | 13130484 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.43 |
P value | 0.000000006 |
Pvalue mlog | 8.22184874961635 |
P value text | |
Or beta | 0.05 |
%95 Ci | [0.032-0.068] unit increase |
Platform | Affymetrix, Illumina [557887] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST002021 |
PubMed ID | 23563607 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23563607 |
Study | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. |
Disease/Trait | Obesity |
Initial sample | 93,015 European ancestry overweight individuals, 32,858 European ancestry class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls |
Replication sample | 65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls |
Region | 4p12 |
Chromosome id | chr4 |
Chromosome position | 45173674 |
Reported gene | GNPDA2 |
Mapped gene | LOC105374441 - PRKRIRP9 |
Upstream gene id | 105374441 |
Downstream gene id | 100131309 |
SNP gene ids | |
Upstream gene distance | 249087 |
Downstream gene distance | 150071 |
SNP risk allele | rs13130484-T |
SNPs | rs13130484 |
Merged | 0 |
SNP id current | 13130484 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.43 |
P value | 0.000000000000000003 |
Pvalue mlog | 17.5228787452803 |
P value text | (Obesity class II) |
Or beta | 1.14 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [~ 2800000] (imputed) |
CNV | N |
Mapped trait | obesity |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0001073 |
Study accession | GCST001953 |
PubMed ID | 26604143 |
Journal | Hum Mol Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26604143 |
Study | Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. |
Disease/Trait | Childhood body mass index |
Initial sample | 34,744 European ancestry children |
Replication sample | 11,313 European ancestry children |
Region | 4p12 |
Chromosome id | chr4 |
Chromosome position | 45173674 |
Reported gene | GNPDA2 |
Mapped gene | LOC105374441 - PRKRIRP9 |
Upstream gene id | 105374441 |
Downstream gene id | 100131309 |
SNP gene ids | |
Upstream gene distance | 249087 |
Downstream gene distance | 150071 |
SNP risk allele | rs13130484-T |
SNPs | rs13130484 |
Merged | 0 |
SNP id current | 13130484 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.44 |
P value | 2E-23 |
Pvalue mlog | 22.698970004336 |
P value text | |
Or beta | 0.067 |
%95 Ci | [0.053-0.081] unit increase |
Platform | Affymetrix, Illumina [2499691] (imputed) |
CNV | N |
Mapped trait | body mass index |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004340 |
Study accession | GCST003177 |