SNP Detail For rs13113591
1.Mapping Information
Human SNP ID rs13113591
Human chromosome chr4
Human SNP position 144567945
Pig chromosome chr8
Pig SNP position 89009416
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144567945
Reported geneIntergenic
Mapped geneLOC105377462 - KRT18P51
Upstream gene id105377462
Downstream gene id391703
SNP gene ids
Upstream gene distance5440
Downstream gene distance4293
SNP risk allelers13113591-T
SNPsrs13113591
Merged0
SNP id current13113591
Contextupstream_gene_variant
Intergenic1
Allele frequency0.351
P value0.00000000000009
Pvalue mlog13.0457574905606
P value text
Or beta0.074
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144567945
Reported geneIntergenic
Mapped geneLOC105377462 - KRT18P51
Upstream gene id105377462
Downstream gene id391703
SNP gene ids
Upstream gene distance5440
Downstream gene distance4293
SNP risk allelers13113591-T
SNPsrs13113591
Merged0
SNP id current13113591
Contextupstream_gene_variant
Intergenic1
Allele frequency0.37
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta0.012
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003265
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144567945
Reported geneIntergenic
Mapped geneLOC105377462 - KRT18P51
Upstream gene id105377462
Downstream gene id391703
SNP gene ids
Upstream gene distance5440
Downstream gene distance4293
SNP risk allelers13113591-T
SNPsrs13113591
Merged0
SNP id current13113591
Contextupstream_gene_variant
Intergenic1
Allele frequency0.349
P value0.00000000000000001
Pvalue mlog17
P value text
Or beta0.018
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264