SNP Detail For rs13082711
1.Mapping Information
Human SNP ID rs13082711
Human chromosome chr3
Human SNP position 27496418
Pig chromosome chr13
Pig SNP position 15585855
2.Annotation Information
PubMed ID21909110
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21909110
StudyGenome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
Disease/TraitBlood pressure
Initial sample74,064 European ancestry individuals
Replication sample48,607 European ancestry individuals
Region3p24.1
Chromosome idchr3
Chromosome position27496418
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance11998
Downstream gene distance16196
SNP risk allelers13082711-T
SNPsrs13082711
Merged0
SNP id current13082711
Contextintergenic_variant
Intergenic1
Allele frequency0.8
P value0.000000005
Pvalue mlog8.30102999566398
P value text(Mean Arterial Pressure)
Or beta0.336
%95 Ci[0.22-0.45] mmHg decrease
PlatformAffymetrix, Illumina, Perlegen [NR] (imputed)
CNVN
Mapped traitmean arterial pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006340
Study accessionGCST001236
PubMed ID21909115
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21909115
StudyGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Disease/TraitDiastolic blood pressure
Initial sample69,395 European ancestry individuals
Replication sampleUp to 133,361 European ancestry individuals
Region3p24.1
Chromosome idchr3
Chromosome position27496418
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance11998
Downstream gene distance16196
SNP risk allelers13082711-T
SNPsrs13082711
Merged0
SNP id current13082711
Contextintergenic_variant
Intergenic1
Allele frequency0.78
P value0.000000004
Pvalue mlog8.39794000867203
P value text
Or beta0.238
%95 Ci[NR] mmHg decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitdiastolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006336
Study accessionGCST001228
PubMed ID21909115
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21909115
StudyGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
Disease/TraitSystolic blood pressure
Initial sample69,395 European ancestry individuals
Replication sampleUp to 133,361 European ancestry individuals
Region3p24.1
Chromosome idchr3
Chromosome position27496418
Reported geneSLC4A7
Mapped geneSLC4A7 - LOC105377005
Upstream gene id9497
Downstream gene id105377005
SNP gene ids
Upstream gene distance11998
Downstream gene distance16196
SNP risk allelers13082711-T
SNPsrs13082711
Merged0
SNP id current13082711
Contextintergenic_variant
Intergenic1
Allele frequency0.78
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta0.315
%95 Ci[NR] mmHg decrease
PlatformAffymetrix, Illumina [~ 2500000] (imputed)
CNVN
Mapped traitsystolic blood pressure
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0006335
Study accessionGCST001227