SNP Detail For rs12991836
1.Mapping Information
Human SNP ID rs12991836
Human chromosome chr2
Human SNP position 144383974
Pig chromosome chr15
Pig SNP position 8031057
2.Annotation Information
PubMed ID23974872
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23974872
StudyGenome-wide association analysis identifies 13 new risk loci for schizophrenia.
Disease/TraitSchizophrenia
Initial sample5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls
Replication sample4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios
Region2q22.3
Chromosome idchr2
Chromosome position144383974
Reported geneZEB2
Mapped geneGTDC1 - ZEB2
Upstream gene id79712
Downstream gene id9839
SNP gene ids
Upstream gene distance51440
Downstream gene distance401
SNP risk allelers12991836-C
SNPsrs12991836
Merged0
SNP id current12991836
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.348
P value0.00000001
Pvalue mlog8
P value text
Or beta1.08
%95 Ci[1.05-1.11]
PlatformAffymetrix, Illumina [9871789]
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST002149
PubMed ID26198764
JournalAm J Med Genet B Neuropsychiatr Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26198764
StudyGenome-wide association study of schizophrenia in Ashkenazi Jews.
Disease/TraitSchizophrenia
Initial sample592 Ashkenazi Jewish ancestry cases, 505 Ashkenazi Jewish ancestry controls, 36,989 cases, 113,075 controls
Replication sampleNA
Region2q22.3
Chromosome idchr2
Chromosome position144383974
Reported geneNR
Mapped geneGTDC1 - ZEB2
Upstream gene id79712
Downstream gene id9839
SNP gene ids
Upstream gene distance51440
Downstream gene distance401
SNP risk allelers12991836-C
SNPsrs12991836
Merged0
SNP id current12991836
Contextdownstream_gene_variant
Intergenic1
Allele frequencyNR
P value0.0000004
Pvalue mlog6.39794000867203
P value text
Or beta1.0526316
%95 Ci[NR]
PlatformIllumina [7158791] (imputed)
CNVN
Mapped traitschizophrenia
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000692
Study accessionGCST003048