SNP Detail For rs12899135
1.Mapping Information
Human SNP ID rs12899135
Human chromosome chr15
Human SNP position 78662037
Pig chromosome chr7
Pig SNP position 52858814
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78662037
Reported geneIntergenic
Mapped geneRPL18P11 - LOC105370913
Upstream gene id390612
Downstream gene id105370913
SNP gene ids
Upstream gene distance396
Downstream gene distance30789
SNP risk allelers12899135-A
SNPsrs12899135
Merged0
SNP id current12899135
Contextintron_variant
Intergenic1
Allele frequency0.608
P value0.00000004
Pvalue mlog7.39794000867203
P value text
Or beta0.054
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78662037
Reported geneIntergenic
Mapped geneRPL18P11 - LOC105370913
Upstream gene id390612
Downstream gene id105370913
SNP gene ids
Upstream gene distance396
Downstream gene distance30789
SNP risk allelers12899135-A
SNPsrs12899135
Merged0
SNP id current12899135
Contextintron_variant
Intergenic1
Allele frequency0.612
P value0.00000001
Pvalue mlog8
P value text
Or beta0.012
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264