SNP Detail For rs12882718
1.Mapping Information
Human SNP ID rs12882718
Human chromosome chr14
Human SNP position 86435710
Pig chromosome chr7
Pig SNP position 115009149
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)
Initial sample371 Japanese ancestry cases, 825 Japanese ancestry controls
Replication sampleNA
Region14q31.3
Chromosome idchr14
Chromosome position86435710
Reported geneLOC100421119
Mapped geneLOC105370607 - LOC283585
Upstream gene id105370607
Downstream gene id283585
SNP gene ids
Upstream gene distance78070
Downstream gene distance470068
SNP risk allelers12882718-T
SNPsrs12882718
Merged0
SNP id current12882718
Contextintergenic_variant
Intergenic1
Allele frequency0.643
P value0.000006
Pvalue mlog5.22184874961635
P value text(Dominant model)
Or beta1.555
%95 Ci[1.283-1.884]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to antineoplastic agent, response to antimicrotubule agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097327, http://www.ebi.ac.uk/efo/EFO_0005260
Study accessionGCST002001