Human SNP ID | rs12777823 |
---|---|
Human chromosome | chr10 |
Human SNP position | 94645745 |
Pig chromosome | chr14 |
Pig SNP position | 145881620 |
PubMed ID | 19706858 |
---|---|
Journal | JAMA |
Link | www.ncbi.nlm.nih.gov/pubmed/19706858 |
Study | Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. |
Disease/Trait | Response to clopidogrel therapy |
Initial sample | 429 Amish individuals |
Replication sample | 140 European ancestry individuals, 83 African American individuals, 4 individuals |
Region | 10q23.33 |
Chromosome id | chr10 |
Chromosome position | 94645745 |
Reported gene | CYP2C18, CYP2C9, CYP2C8, CYP2C19 |
Mapped gene | HELLS - CYP2C18 |
Upstream gene id | 3070 |
Downstream gene id | 1562 |
SNP gene ids | |
Upstream gene distance | 43646 |
Downstream gene distance | 37749 |
SNP risk allele | rs12777823-? |
SNPs | rs12777823 |
Merged | 0 |
SNP id current | 12777823 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.17 |
P value | 0.0000000000002 |
Pvalue mlog | 12.698970004336 |
P value text | (Amish) |
Or beta | |
%95 Ci | |
Platform | Affymetrix [400230] |
CNV | N |
Mapped trait | response to platelet aggregation inhibitor |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0061478 |
Study accession | GCST000467 |
PubMed ID | 23755828 |
Journal | Lancet |
Link | www.ncbi.nlm.nih.gov/pubmed/23755828 |
Study | Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. |
Disease/Trait | Warfarin maintenance dose |
Initial sample | 533 African American individuals |
Replication sample | 432 African American individuals |
Region | 10q23.33 |
Chromosome id | chr10 |
Chromosome position | 94645745 |
Reported gene | CYP2C, CYP2C18, CYP2C9, CYP2C8, CYP2C19 |
Mapped gene | HELLS - CYP2C18 |
Upstream gene id | 3070 |
Downstream gene id | 1562 |
SNP gene ids | |
Upstream gene distance | 43646 |
Downstream gene distance | 37749 |
SNP risk allele | rs12777823-? |
SNPs | rs12777823 |
Merged | 0 |
SNP id current | 12777823 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000000000005 |
Pvalue mlog | 11.3010299956639 |
P value text | |
Or beta | |
%95 Ci | |
Platform | Illumina [3044177] (imputed) |
CNV | N |
Mapped trait | response to anticoagulant |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0061476 |
Study accession | GCST002061 |