SNP Detail For rs12723025
1.Mapping Information
Human SNP ID rs12723025
Human chromosome chr1
Human SNP position 223789817
Pig chromosome chr10
Pig SNP position 24468855
2.Annotation Information
PubMed ID26121980
JournalBMC Genomics
Linkwww.ncbi.nlm.nih.gov/pubmed/26121980
StudyGenome-wide association analysis identified splicing single nucleotide polymorphism in CFLAR predictive of triptolide chemo-sensitivity.
Disease/TraitTriptolide cytotoxicity
Initial sample55 European ancestry lymphoblastoid cell lines
Replication sampleNA
Region1q41
Chromosome idchr1
Chromosome position223789817
Reported geneTP53BP2
Mapped geneTP53BP2
Upstream gene id
Downstream gene id
SNP gene ids7159
Upstream gene distance
Downstream gene distance
SNP risk allelers12723025-?
SNPsrs12723025
Merged
SNP id current12723025
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.000009
Pvalue mlog5.04575749056067
P value text
Or beta0.56
%95 Ciunit increase
PlatformNR [at least 1978803] (imputed)
CNVN
Mapped traitresponse to triptolide, cytotoxicity measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0007662, http://www.ebi.ac.uk/efo/EFO_0006952
Study accessionGCST003008