Human SNP ID | rs12722489 |
---|---|
Human chromosome | chr10 |
Human SNP position | 6060049 |
Pig chromosome | chr10 |
Pig SNP position | 71065902 |
PubMed ID | 17660530 |
---|---|
Journal | N Engl J Med |
Link | www.ncbi.nlm.nih.gov/pubmed/17660530 |
Study | Risk alleles for multiple sclerosis identified by a genomewide study. |
Disease/Trait | Multiple sclerosis |
Initial sample | 931 European ancestry trios, 2,431 European ancestry controls |
Replication sample | 609 European ancestry trios, 2,322 European ancestry cases, 2,987 European ancestry controls |
Region | 10p15.1 |
Chromosome id | chr10 |
Chromosome position | 6060049 |
Reported gene | IL2RA |
Mapped gene | IL2RA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3559 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12722489-C |
SNPs | rs12722489 |
Merged | 0 |
SNP id current | 12722489 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.85 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | |
Or beta | 1.25 |
%95 Ci | [1.11-1.36] |
Platform | Affymetrix [334923] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST000062 |
PubMed ID | 22190364 |
Journal | Ann Neurol |
Link | www.ncbi.nlm.nih.gov/pubmed/22190364 |
Study | Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. |
Disease/Trait | Multiple sclerosis |
Initial sample | 5,545 European ancestry cases, 12,153 European ancestry controls |
Replication sample | NA |
Region | 10p15.1 |
Chromosome id | chr10 |
Chromosome position | 6060049 |
Reported gene | IL2RA |
Mapped gene | IL2RA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3559 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12722489-C |
SNPs | rs12722489 |
Merged | 0 |
SNP id current | 12722489 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.85 |
P value | 0.00000004 |
Pvalue mlog | 7.39794000867203 |
P value text | |
Or beta | 1.23 |
%95 Ci | [NR] |
Platform | Affymetrix, Illumina [2529394] |
CNV | N |
Mapped trait | multiple sclerosis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003885 |
Study accession | GCST001341 |
PubMed ID | 21102463 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21102463 |
Study | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn__s disease susceptibility loci. |
Disease/Trait | Crohn__s disease |
Initial sample | 6,333 European ancestry cases, 15,056 European ancestry controls |
Replication sample | 15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios |
Region | 10p15.1 |
Chromosome id | chr10 |
Chromosome position | 6060049 |
Reported gene | IL2RA |
Mapped gene | IL2RA |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 3559 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs12722489-C |
SNPs | rs12722489 |
Merged | 0 |
SNP id current | 12722489 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.852 |
P value | 0.000000003 |
Pvalue mlog | 8.52287874528033 |
P value text | |
Or beta | 1.11 |
%95 Ci | [1.05-1.16] |
Platform | Affymetrix, Illumina [953241] (imputed) |
CNV | N |
Mapped trait | Crohn__s disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000384 |
Study accession | GCST000879 |