SNP Detail For rs1262476
1.Mapping Information
Human SNP ID rs1262476
Human chromosome chr6
Human SNP position 126665850
Pig chromosome chr1
Pig SNP position 40234188
2.Annotation Information
PubMed ID24945404
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24945404
StudyPhenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Disease/TraitBone mineral density (paediatric, upper limb)
Initial sample8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children
Replication sampleNA
Region6q22.32
Chromosome idchr6
Chromosome position126665850
Reported geneCENPW, RSPO3
Mapped genePRELID1P1 - RPS4XP9
Upstream gene id728666
Downstream gene id442257
SNP gene ids
Upstream gene distance21452
Downstream gene distance17163
SNP risk allelers1262476-G
SNPsrs1262476
Merged0
SNP id current1262476
Contextintergenic_variant
Intergenic1
Allele frequency0.77
P value0.000000003
Pvalue mlog8.52287874528033
P value text
Or beta0.104
%95 Ci[0.069-0.139] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST002496
PubMed ID24945404
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24945404
StudyPhenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Disease/TraitBone mineral density (paediatric, upper limb)
Initial sample8,007 European ancestry children, 289 Surinamese ancestry children, 300 Turkish ancestry children, 232 Moroccan ancestry children, 588 children
Replication sampleNA
Region6q22.32
Chromosome idchr6
Chromosome position126665850
Reported geneCENPW, RSPO3
Mapped genePRELID1P1 - RPS4XP9
Upstream gene id728666
Downstream gene id442257
SNP gene ids
Upstream gene distance21452
Downstream gene distance17163
SNP risk allelers1262476-G
SNPsrs1262476
Merged0
SNP id current1262476
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.00000004
Pvalue mlog7.39794000867203
P value text(EA)
Or beta0.1045
%95 Ci[0.067-0.142] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitbone density
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003923
Study accessionGCST002496