SNP Detail For rs12603526
1.Mapping Information
Human SNP ID rs12603526
Human chromosome chr17
Human SNP position 897353
Pig chromosome chr12
Pig SNP position 49131939
2.Annotation Information
PubMed ID24836286
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24836286
StudyLarge-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Disease/TraitColorectal cancer
Initial sample2,098 East Asian ancestry cases, 6,172 East Asian ancestry controls
Replication sample12,865 East Asian ancestry cases, 25,773 East Asian ancestry controls, up to 16,984 European ancestry cases, up to 18,262 European ancestry controls
Region17p13.3
Chromosome idchr17
Chromosome position897353
Reported geneNXN
Mapped geneNXN
Upstream gene id
Downstream gene id
SNP gene ids64359
Upstream gene distance
Downstream gene distance
SNP risk allelers12603526-C
SNPsrs12603526
Merged0
SNP id current12603526
Contextintron_variant
Intergenic0
Allele frequency0.3
P value0.00000003
Pvalue mlog7.52287874528033
P value text(East Asian)
Or beta1.1
%95 Ci[1.06-1.14]
PlatformAffymetrix, Illumina [2400000] (imputed)
CNVN
Mapped traitcolorectal cancer
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005842
Study accessionGCST002454