SNP Detail For rs1260333
1.Mapping Information
Human SNP ID rs1260333
Human chromosome chr2
Human SNP position 27525757
Pig chromosome chr3
Pig SNP position 118826228
2.Annotation Information
PubMed ID20864672
JournalArterioscler Thromb Vasc Biol
Linkwww.ncbi.nlm.nih.gov/pubmed/20864672
StudyGenetic variants influencing circulating lipid levels and risk of coronary artery disease.
Disease/TraitTriglycerides
Initial sampleup to 17,723 European ancestry individuals
Replication sampleup to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals
Region2p23.3
Chromosome idchr2
Chromosome position27525757
Reported geneGCKR
Mapped geneGCKR - C2orf16
Upstream gene id2646
Downstream gene id84226
SNP gene ids
Upstream gene distance2068
Downstream gene distance50765
SNP risk allelers1260333-C
SNPsrs1260333
Merged0
SNP id current1260333
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.55
P value2E-19
Pvalue mlog18.698970004336
P value text
Or beta0.05
%95 Ci[0.04-0.06] unit decrease
PlatformAffymetrix, Illumina, Perlegen [2155369] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST000809
PubMed ID26582766
JournalCirc Cardiovasc Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26582766
StudyGenetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
Disease/TraitTriglycerides
Initial sample8,344 Han Chinese ancestry individuals
Replication sample14,739 Han Chinese ancestry individuals
Region2p23.3
Chromosome idchr2
Chromosome position27525757
Reported geneGCKR
Mapped geneGCKR - C2orf16
Upstream gene id2646
Downstream gene id84226
SNP gene ids
Upstream gene distance2068
Downstream gene distance50765
SNP risk allelers1260333-A
SNPsrs1260333
Merged0
SNP id current1260333
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.52
P value2E-21
Pvalue mlog20.698970004336
P value text
Or beta0.022
%95 Ci[0.018-0.026] unit increase
PlatformAffymetrix, Illumina [2573667] (imputed)
CNVN
Mapped traittriglyceride measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004530
Study accessionGCST003217
PubMed ID26582766
JournalCirc Cardiovasc Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26582766
StudyGenetic Susceptibility to Lipid Levels and Lipid Change Over Time and Risk of Incident Hyperlipidemia in Chinese Populations.
Disease/TraitCholesterol, total
Initial sample8,344 Han Chinese ancestry individuals
Replication sample14,739 Han Chinese ancestry individuals
Region2p23.3
Chromosome idchr2
Chromosome position27525757
Reported geneGCKR
Mapped geneGCKR - C2orf16
Upstream gene id2646
Downstream gene id84226
SNP gene ids
Upstream gene distance2068
Downstream gene distance50765
SNP risk allelers1260333-A
SNPsrs1260333
Merged0
SNP id current1260333
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.52
P value0.00000003
Pvalue mlog7.52287874528033
P value text
Or beta1.773
%95 Ci[1.15-2.4] unit increase
PlatformAffymetrix, Illumina [2573667] (imputed)
CNVN
Mapped traittotal cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004574
Study accessionGCST003214