SNP Detail For rs12586420
1.Mapping Information
Human SNP ID rs12586420
Human chromosome chr14
Human SNP position 86302020
Pig chromosome chr7
Pig SNP position 114875685
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region14q31.3
Chromosome idchr14
Chromosome position86302020
Reported geneIntergenic
Mapped geneLOC101928767 - LOC105370607
Upstream gene id101928767
Downstream gene id105370607
SNP gene ids
Upstream gene distance172242
Downstream gene distance29563
SNP risk allelers12586420-A
SNPsrs12586420
Merged0
SNP id current12586420
Contextintergenic_variant
Intergenic1
Allele frequency0.351
P value0.0000003
Pvalue mlog6.52287874528033
P value text(AA)
Or beta0.095
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262